5O7S

Crystal structure of a single chain monellin mutant (Y65R) pH 8.3

Summary for 5O7S

• Entry DOI: 10.2210/pdb5o7s/pdb
• Descriptor: Monellin chain B,Monellin chain A, SULFATE ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: plant protein, sweet protein, sweetener
• Biological source: Dioscoreophyllum cumminsii (Serendipity berry); More
• Total number of polymer chains: 2
• Total formula weight: 22765.93

Authors

Pica, A.,Merlino, A. (deposition date: 2017-06-09, release date: 2018-01-10, Last modification date: 2024-01-17)

Primary citation

Pica, A.,Leone, S.,Di Girolamo, R.,Donnarumma, F.,Emendato, A.,Rega, M.F.,Merlino, A.,Picone, D.
pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862:808-815, 2017

PubMed Abstract: MNEI and its variant Y65R-MNEI are sweet proteins with potential applications as sweeteners in food industry. Also, they are often used as model systems for folding and aggregation studies.

PubMed: 29288772
DOI: 10.1016/j.bbagen.2017.12.012

Experimental method

X-RAY DIFFRACTION (2.02 Å)