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1PRE
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BU of 1pre by Molmil
PROAEROLYSIN
分子名称: PROAEROLYSIN
著者Parker, M.W, Buckley, J.T, Postma, J.P.M, Tucker, A.D, Tsernoglou, D.
登録日1995-09-15
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states.
Nature, 367, 1994
1COL
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BU of 1col by Molmil
REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION
分子名称: COLICIN A
著者Parker, M.W, Postma, J.P.M, Pattus, F, Tucker, A.D, Tsernoglou, D.
登録日1991-07-06
公開日1992-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Refined structure of the pore-forming domain of colicin A at 2.4 A resolution.
J.Mol.Biol., 224, 1992
1Z52
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BU of 1z52 by Molmil
Proaerolysin Mutant W373L
分子名称: Aerolysin
著者Parker, M.W, Feil, S.C, Tang, J.W.
登録日2005-03-16
公開日2006-03-07
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal Structure of Proaerolysin at 2.3 A Resolution and Structural Analyses of Single-site Mutants as a Basis for Understanding Membrane Insertion of the Toxin
To be Published
5DHL
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BU of 5dhl by Molmil
Crystal structure of Toxin, mutant N197W
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
著者Parker, M.W, Gorman, M.A, Lawrence, S.L.
登録日2015-08-31
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structure of mutant toxin
To Be Published
5DIM
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BU of 5dim by Molmil
Mutant toxin in 'native' space group
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
著者Parker, M.W, Gorman, M.A, Lawrence, S.L.
登録日2015-09-01
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structure of mutant toxin at 3.32 Angstrom resolution
To Be Published
4QDQ
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BU of 4qdq by Molmil
Physical basis for Nrp2 ligand binding
分子名称: GLYCEROL, Neuropilin-2, SULFATE ION
著者Parker, M.W, Vander Kooi, C.W.
登録日2014-05-14
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form.
Structure, 23, 2015
4QDR
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BU of 4qdr by Molmil
Physical basis for Nrp2 ligand binding
分子名称: Neuropilin-2
著者Parker, M.W, Vander Kooi, C.W.
登録日2014-05-14
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form.
Structure, 23, 2015
4QDS
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BU of 4qds by Molmil
Physical basis for Nrp2 ligand binding
分子名称: ACETATE ION, GLYCEROL, Neuropilin-2
著者Parker, M.W, Vander Kooi, C.W.
登録日2014-05-14
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form.
Structure, 23, 2015
4NKQ
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BU of 4nkq by Molmil
Structure of a Cytokine Receptor Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Granulocyte-macrophage colony-stimulating factor, ...
著者Parker, M.W, Broughton, S.E.
登録日2013-11-13
公開日2015-09-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling.
Structure, 24, 2016
4ZGH
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BU of 4zgh by Molmil
Structure of Sugar Binding Protein Pneumolysin
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GOLD (I) CYANIDE ION, ...
著者Parker, M.W, Feil, S.C, Morton, C.
登録日2015-04-23
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation.
Sci Rep, 5, 2015
7SIA
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BU of 7sia by Molmil
HIV Integrase core domain in complex with inhibitor 2-[2-(2-{3-[(4-{2-[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)formamido]ethyl}piperazin-1-yl)methyl]phenyl}ethynyl)-5-methyl-1-benzofuran-3-yl]acetic acid
分子名称: (2-{[3-({4-[2-(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzamido)ethyl]piperazin-1-yl}methyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid, IODIDE ION, Integrase, ...
著者Gorman, M.A, Parker, M.W.
登録日2021-10-12
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献HIV Integrase core domain in complex with inhibitor
To Be Published
1FHE
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BU of 1fhe by Molmil
GLUTATHIONE TRANSFERASE (FH47) FROM FASCIOLA HEPATICA
分子名称: GLUTATHIONE, GLUTATHIONE TRANSFERASE
著者Rossjohn, J, Parker, M.W.
登録日1997-07-24
公開日1998-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase.
J.Mol.Biol., 273, 1997
1MD3
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BU of 1md3 by Molmil
A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase
著者Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W.
登録日2002-08-06
公開日2002-08-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
1MWP
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BU of 1mwp by Molmil
N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN
分子名称: AMYLOID A4 PROTEIN
著者Rossjohn, J, Cappai, R, Feil, S.C, Henry, A, McKinstry, W.J, Galatis, D, Hesse, L, Multhaup, G, Beyreuther, K, Masters, C.L, Parker, M.W.
登録日1999-03-09
公開日2000-03-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
Nat.Struct.Biol., 6, 1999
4FHA
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BU of 4fha by Molmil
Structure of Dihydrodipicolinate Synthase from Streptococcus pneumoniae,bound to pyruvate and lysine
分子名称: Dihydrodipicolinate synthase, LYSINE, SODIUM ION
著者Perugini, M.A, Dogovski, C, Parker, M.W, Gorman, M.A.
登録日2012-06-06
公開日2013-09-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
To be Published
3BKJ
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BU of 3bkj by Molmil
Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16)
分子名称: Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
著者Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
登録日2007-12-06
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3BKM
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BU of 3bkm by Molmil
Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)
分子名称: SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ...
著者Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
登録日2007-12-07
公開日2008-04-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3U0W
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BU of 3u0w by Molmil
AD related murine antibody Fragment
分子名称: Fab Heavy Chain, Ig gamma-1 chain C region, Fab Light Chain, ...
著者Miles, L.A, Crespi, G.A.N, Parker, M.W.
登録日2011-09-29
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of an AD related antibody
To be Published
6WC8
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BU of 6wc8 by Molmil
HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid
分子名称: IODIDE ION, Integrase, SULFATE ION, ...
著者Gorman, M.A, Parker, M.W.
登録日2020-03-29
公開日2021-03-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献HIV Integrase core domain in complex with inhibitor
To Be Published
6WE7
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BU of 6we7 by Molmil
HIV Integrase core domain in complex with inhibitor 3-methyl-2-{5-methyl-2-[2-(thiophen-2-yl)ethynyl]-1- benzofuran-3-yl}butanoic acid
分子名称: (2S)-3-methyl-2-{5-methyl-2-[(thiophen-2-yl)ethynyl]-1-benzofuran-3-yl}butanoic acid, IODIDE ION, Integrase, ...
著者Gorman, M.A, Parker, M.W.
登録日2020-04-01
公開日2021-04-07
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献HIV Integrase core domain in complex with inhibitor
To Be Published
6WM8
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BU of 6wm8 by Molmil
Proliferation-Associated protein 2G4 (PA2G4)
分子名称: Proliferation-associated protein 2G4, SULFATE ION
著者Gorman, M.A, Stevenson, B.W, Parker, M.W.
登録日2020-04-20
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献PA2G4: A Structural Perspective
To Be Published
4Y0G
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BU of 4y0g by Molmil
beta2 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK)
分子名称: 5'-AMP-activated protein kinase subunit beta-2, GLYCEROL
著者Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M.
登録日2015-02-06
公開日2015-04-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Biochem.J., 468, 2015
1FW1
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BU of 1fw1 by Molmil
Glutathione transferase zeta/maleylacetoacetate isomerase
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLUTATHIONE, GLUTATHIONE TRANSFERASE ZETA, ...
著者Polekhina, G, Board, P.G, Blackburn, A.C, Parker, M.W.
登録日2000-09-20
公開日2001-09-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity.
Biochemistry, 40, 2001
6XD4
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BU of 6xd4 by Molmil
CDC-like protein
分子名称: ACETATE ION, Hemolysin, SODIUM ION
著者Morton, C.J, Parker, M.W, Lawrence, S.L, Johnstone, B.A, Tweten, R.K.
登録日2020-06-09
公開日2021-04-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins.
Mbio, 11, 2020
2R4V
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BU of 2r4v by Molmil
Structure of human CLIC2, crystal form A
分子名称: Chloride intracellular channel protein 2, GLUTATHIONE
著者Hansen, G, Cromer, B.A, Gorman, M.A, Parker, M.W.
登録日2007-09-02
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the Janus Protein Human CLIC2
J.Mol.Biol., 374, 2007

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