8FAX
| Fab 1249A8-MERS Stem Helix Complex | 分子名称: | 1249A8-HC, 1249A8-LC, CHLORIDE ION, ... | 著者 | Deshpande, A, Schormann, N, Piepenbrink, M.S, Martinez-Sobrido, L, Kobie, J.J, Walter, M.R. | 登録日 | 2022-11-28 | 公開日 | 2023-05-03 | 最終更新日 | 2023-07-19 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and epitope of a neutralizing monoclonal antibody that targets the stem helix of beta coronaviruses. Febs J., 290, 2023
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2I9F
| Structure of the equine arterivirus nucleocapsid protein | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | 著者 | Deshpande, A, Wang, S, Walsh, M, Dokland, T. | 登録日 | 2006-09-05 | 公開日 | 2007-05-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement. Acta Crystallogr.,Sect.D, 63, 2007
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1Z55
| Effect of alcohols on protein hydration | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Deshpande, A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-03-17 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1YKX
| Effect of alcohols on protein hydration | 分子名称: | CHLORIDE ION, ETHANOL, Lysozyme C, ... | 著者 | Deshpande, A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1YKY
| Effect of alcohols on protein hydration | 分子名称: | 1-BUTANOL, CHLORIDE ION, Lysozyme C, ... | 著者 | Deshpande, A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1YKZ
| Effect of alcohols on protein hydration | 分子名称: | CHLORIDE ION, Lysozyme C, PENTANAL, ... | 著者 | Deshpande, A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1YL0
| Effect of alcohols on protein hydration | 分子名称: | CHLORIDE ION, ISOPROPYL ALCOHOL, Lysozyme C, ... | 著者 | Deshpande, A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1I5I
| THE C18S MUTANT OF BOVINE (GAMMA-B)-CRYSTALLIN | 分子名称: | (GAMMA-B) CRYSTALLIN | 著者 | Zarutskie, J.A, Asherie, N, Pande, J, Pande, A, Lomakin, J, Lomakin, A, Ogun, O, Stern, L.J, King, J.A, Benedek, G.B. | 登録日 | 2001-02-27 | 公開日 | 2001-03-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Enhanced crystallization of the Cys18 to Ser mutant of bovine gammaB crystallin. J.Mol.Biol., 314, 2001
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2NBR
| The Solution Structure of Human gammaC-crystallin | 分子名称: | Gamma-crystallin C | 著者 | Dixit, K, Pande, A, Pande, J, Sarma, S.P. | 登録日 | 2016-03-12 | 公開日 | 2016-06-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear Magnetic Resonance Structure of a Major Lens Protein, Human gamma C-Crystallin: Role of the Dipole Moment in Protein Solubility. Biochemistry, 55, 2016
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1VZU
| Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE | 分子名称: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K. | 登録日 | 2004-05-27 | 公開日 | 2004-07-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology, 14, 2004
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1VZX
| Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE | 分子名称: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K. | 登録日 | 2004-05-28 | 公開日 | 2004-07-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology, 14, 2004
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1O7O
| Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis | 分子名称: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ... | 著者 | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K. | 登録日 | 2002-11-11 | 公開日 | 2003-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry, 42, 2003
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1O7Q
| Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis | 分子名称: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K. | 登録日 | 2002-11-12 | 公開日 | 2003-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity. Biochemistry, 42, 2003
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7JXG
| Structural model for Fe-containing human acireductone dioxygenase | 分子名称: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, FE (II) ION | 著者 | Pochapsky, T.C, Liu, X, Deshpande, A, Ringe, D, Garber, A, Ryan, J. | 登録日 | 2020-08-27 | 公開日 | 2020-11-18 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A Model for the Solution Structure of Human Fe(II)-Bound Acireductone Dioxygenase and Interactions with the Regulatory Domain of Matrix Metalloproteinase I (MMP-I). Biochemistry, 59, 2020
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1VZT
| ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, X, Acharya, K.R, Brew, K. | 登録日 | 2004-05-26 | 公開日 | 2005-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity. Biochemistry, 42, 2003
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3VW7
| Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ... | 著者 | Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K. | 登録日 | 2012-08-07 | 公開日 | 2012-12-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High-resolution crystal structure of human protease-activated receptor 1 Nature, 492, 2012
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1YL1
| Effect of alcohols on protein hydration | 分子名称: | Lysozyme C, SODIUM ION, TRIFLUOROETHANOL | 著者 | Deshpande, A.A, Nimsadkar, S, Mande, S.C. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr.,Sect.D, 61, 2005
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1H4A
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1HK0
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7MJU
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6ZJZ
| Discovery of M5049: a novel selective TLR7/8 inhibitor for treatment of autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile, FORMIC ACID, ... | 著者 | Musil, D, Lehman, M, Strauss, J. | 登録日 | 2020-06-29 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity. J.Pharmacol.Exp.Ther., 376, 2021
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3LQM
| Structure of the IL-10R2 Common Chain | 分子名称: | GLYCEROL, Interleukin-10 receptor subunit beta, SULFATE ION | 著者 | Yoon, S.I, Walter, M.R. | 登録日 | 2010-02-09 | 公開日 | 2010-05-26 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structure and mechanism of receptor sharing by the IL-10R2 common chain. Structure, 18, 2010
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3BX4
| Crystal structure of the snake venom toxin aggretin | 分子名称: | Aggretin alpha chain, Aggretin beta chain, GLYCEROL, ... | 著者 | Hooley, E, Papagrigoriou, E, Navdaev, A, Pandey, A, Clemetson, J.M, Clemetson, K.J, Emsley, J. | 登録日 | 2008-01-11 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure. Biochemistry, 47, 2008
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4BAE
| Optimisation of pyrroleamides as mycobacterial GyrB ATPase inhibitors: Structure Activity Relationship and in vivo efficacy in the mouse model of tuberculosis | 分子名称: | 2-[(3S,4R)-4-[(3-bromanyl-4-chloranyl-5-methyl-1H-pyrrol-2-yl)carbonylamino]-3-methoxy-piperidin-1-yl]-4-(2-methyl-1,2,4-triazol-3-yl)-1,3-thiazole-5-carboxylic acid, CALCIUM ION, DNA GYRASE SUBUNIT B, ... | 著者 | Read, J.A, Gingell, H.G, Madhavapeddi, P. | 登録日 | 2012-09-13 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Optimization of Pyrrolamides as Mycobacterial Gyrb ATPase Inhibitors: Structure Activity Relationship and in Vivo Efficacy in the Mouse Model of Tuberculosis. Antimicrob.Agents Chemother., 58, 2014
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2LOV
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