6MXO
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![BU of 6mxo by Molmil](/molmil-images/mine/6mxo) | Structure of HPoleta incorporating dCTP opposite the 3-prime Pt(DACH)-GG | 分子名称: | (cyclohex-1-ene-1,2-diamine)platinum(2+), 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... | 著者 | Ouzon-Shubeita, H, Lee, S. | 登録日 | 2018-10-31 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta. Biochem. J., 476, 2019
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5CHZ
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![BU of 5chz by Molmil](/molmil-images/mine/5chz) | |
6U2O
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![BU of 6u2o by Molmil](/molmil-images/mine/6u2o) | |
6U6B
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![BU of 6u6b by Molmil](/molmil-images/mine/6u6b) | Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... | 著者 | Ouzon-Shubeita, H, Vilas, C.K, Lee, S. | 登録日 | 2019-08-29 | 公開日 | 2020-09-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.108 Å) | 主引用文献 | Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion. Biochem.J., 477, 2020
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4OFH
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![BU of 4ofh by Molmil](/molmil-images/mine/4ofh) | |
4OFE
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![BU of 4ofe by Molmil](/molmil-images/mine/4ofe) | |
4OFA
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![BU of 4ofa by Molmil](/molmil-images/mine/4ofa) | |
6VJW
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![BU of 6vjw by Molmil](/molmil-images/mine/6vjw) | Crystal structure of WT hMBD4 complexed with T:G mismatch DNA | 分子名称: | DNA (5'-D(*CP*CP*AP*GP*CP*GP*(ORP)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), Methyl-CpG-binding domain protein 4 | 著者 | Jung, H, Lee, S. | 登録日 | 2020-01-17 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4. Biochem.J., 477, 2020
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4F4B
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![BU of 4f4b by Molmil](/molmil-images/mine/4f4b) | Structure of OSH4 with a cholesterol analog | 分子名称: | (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1 | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | 登録日 | 2012-05-10 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4. Steroids, 78, 2013
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4FES
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![BU of 4fes by Molmil](/molmil-images/mine/4fes) | Structure of OSH4 in complex with cholesterol analogs | 分子名称: | (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one, Protein KES1 | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | 登録日 | 2012-05-30 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4. Steroids, 78, 2013
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5HHI
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![BU of 5hhi by Molmil](/molmil-images/mine/5hhi) | Structure of human DNA polymerase beta Host-Guest complexed with CBZ-platinated N7-G | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Lee, S, Koag, M.-C. | 登録日 | 2016-01-11 | 公開日 | 2017-01-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.517 Å) | 主引用文献 | Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Chem Biol Drug Des, 91, 2018
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5HHH
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![BU of 5hhh by Molmil](/molmil-images/mine/5hhh) | Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Koag, M.-C, Lee, S. | 登録日 | 2016-01-11 | 公開日 | 2017-01-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.363 Å) | 主引用文献 | Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Chem Biol Drug Des, 91, 2018
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4O5C
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4O5E
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![BU of 4o5e by Molmil](/molmil-images/mine/4o5e) | |
4O5K
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![BU of 4o5k by Molmil](/molmil-images/mine/4o5k) | |
4P2H
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![BU of 4p2h by Molmil](/molmil-images/mine/4p2h) | |