3ISI
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3MDJ
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![BU of 3mdj by Molmil](/molmil-images/mine/3mdj) | ER Aminopeptidase, ERAP1, Bound to the Zinc Aminopeptidase Inhibitor, Bestatin | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nguyen, T.T, Stern, L.J. | 登録日 | 2010-03-30 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat.Struct.Mol.Biol., 18, 2011
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7SBN
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7SBM
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7Q5C
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![BU of 7q5c by Molmil](/molmil-images/mine/7q5c) | Crystal structure of OmpG in space group 96 | 分子名称: | Outer membrane porin G, SODIUM ION, TETRAETHYLENE GLYCOL, ... | 著者 | Nguyen, T.T.M, Khan, A.R, Barringer, R, McManus, J.J, Race, P.R. | 登録日 | 2021-11-03 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.717 Å) | 主引用文献 | Experimental phase diagrams to optimise OmpG To Be Published
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7ALM
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7AIA
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![BU of 7aia by Molmil](/molmil-images/mine/7aia) | Complex of human GDAP1 with hexadecanedioic acid | 分子名称: | ETHANOL, GLYCEROL, Ganglioside-induced differentiation-associated protein 1, ... | 著者 | Nguyen, G.T.T, Sutinen, A, Kursula, P. | 登録日 | 2020-09-26 | 公開日 | 2021-02-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations. Front Mol Biosci, 7, 2020
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4C7B
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![BU of 4c7b by Molmil](/molmil-images/mine/4c7b) | Complex of human Sirt3 with Bromo-Resveratrol and Fluor-De-Lys peptide | 分子名称: | 5-[(E)-2-(4-bromophenyl)ethenyl]benzene-1,3-diol, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Nguyen, G.T.T, Gertz, M, Weyand, M, Steegborn, C. | 登録日 | 2013-09-20 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of Sirt3 Complexes with 4'-Bromo-Resveratrol Reveal Binding Sites and Inhibition Mechanism. Chem.Biol., 20, 2013
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4BN4
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![BU of 4bn4 by Molmil](/molmil-images/mine/4bn4) | Structure of human SIRT3 in complex with ADP-ribose | 分子名称: | 2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanoic acid, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL, ... | 著者 | Nguyen, G.T.T, Schaefer, S, Gertz, M, Weyand, M, Steegborn, C. | 登録日 | 2013-05-13 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structures of Human Sirtuin 3 Complexes with Adp-Ribose and with Carba-Nad+ and Srt1720: Binding Details and Inhibition Mechanism Acta Crystallogr.,Sect.D, 69, 2013
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4C78
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![BU of 4c78 by Molmil](/molmil-images/mine/4c78) | Complex of human Sirt3 with Bromo-Resveratrol and ACS2 peptide | 分子名称: | 5-[(E)-2-(4-bromophenyl)ethenyl]benzene-1,3-diol, ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL, ... | 著者 | Nguyen, G.T.T, Gertz, M, Weyand, M, Steegborn, C. | 登録日 | 2013-09-19 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of Sirt3 Complexes with 4'-Bromo-Resveratrol Reveal Binding Sites and Inhibition Mechanism. Chem.Biol., 20, 2013
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4BN5
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![BU of 4bn5 by Molmil](/molmil-images/mine/4bn5) | Structure of human SIRT3 in complex with SRT1720 inhibitor | 分子名称: | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, N-{2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}quinoxaline-2-carboxamide, ... | 著者 | Nguyen, G.T.T, Schaefer, S, Gertz, M, Weyand, M, Steegborn, C. | 登録日 | 2013-05-13 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structures of Human Sirtuin 3 Complexes with Adp-Ribose and with Carba-Nad+ and Srt1720: Binding Details and Inhibition Mechanism Acta Crystallogr.,Sect.D, 69, 2013
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3HK5
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![BU of 3hk5 by Molmil](/molmil-images/mine/3hk5) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate | 分子名称: | CARBONATE ION, CHLORIDE ION, D-arabinaric acid, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3HK8
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![BU of 3hk8 by Molmil](/molmil-images/mine/3hk8) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinohydroxamate | 分子名称: | CARBONATE ION, CHLORIDE ION, D-arabinohydroxamic acid, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3HKA
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![BU of 3hka by Molmil](/molmil-images/mine/3hka) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Fructuronate | 分子名称: | CARBONATE ION, CHLORIDE ION, D-fructuronic acid, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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2IPK
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![BU of 2ipk by Molmil](/molmil-images/mine/2ipk) | Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2 | 分子名称: | Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ... | 著者 | Nguyen, T.T, Stern, L.J. | 登録日 | 2006-10-12 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat.Chem.Biol., 3, 2007
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3TIE
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![BU of 3tie by Molmil](/molmil-images/mine/3tie) | Crystal structure of the vaccinia derived peptide A11R in complex with the murine MHC CLASS I H-2 KB | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | 著者 | Nguyen, T.T, Shen, Z.T, Stern, L.J. | 登録日 | 2011-08-20 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells. J.Immunol., 191, 2013
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3TID
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![BU of 3tid by Molmil](/molmil-images/mine/3tid) | Crystal structure of the LCMV derived peptide GP34 in complex with the murine mhc class I H-2 Kb | 分子名称: | ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Nguyen, T.T, Shen, Z.T, Stern, L.J. | 登録日 | 2011-08-20 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells. J.Immunol., 191, 2013
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3HK9
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![BU of 3hk9 by Molmil](/molmil-images/mine/3hk9) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Glucuronate | 分子名称: | CARBONATE ION, CHLORIDE ION, D-glucuronic acid, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3HK7
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![BU of 3hk7 by Molmil](/molmil-images/mine/3hk7) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate, monoclinic crystal form | 分子名称: | CARBONATE ION, CHLORIDE ION, D-arabinaric acid, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3ITC
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![BU of 3itc by Molmil](/molmil-images/mine/3itc) | Crystal structure of Sco3058 with bound citrate and glycerol | 分子名称: | CITRIC ACID, GLYCEROL, ZINC ION, ... | 著者 | Nguyen, T.T, Cummings, J.A, Tsai, C.-L, Barondeau, D.P, Raushel, F.M. | 登録日 | 2009-08-28 | 公開日 | 2010-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase Biochemistry, 49, 2010
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7B2G
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3EUV
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![BU of 3euv by Molmil](/molmil-images/mine/3euv) | Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP | 分子名称: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | 著者 | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | 登録日 | 2008-10-11 | 公開日 | 2009-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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3EU5
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![BU of 3eu5 by Molmil](/molmil-images/mine/3eu5) | Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP | 分子名称: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | 著者 | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | 登録日 | 2008-10-09 | 公開日 | 2009-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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8SZJ
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![BU of 8szj by Molmil](/molmil-images/mine/8szj) | Human glutaminase C (Y466W) with L-Gln and Pi, filamentous form | 分子名称: | GLUTAMINE, Glutaminase kidney isoform, mitochondrial, ... | 著者 | Feng, S, Aplin, C, Nguyen, T.-T.T, Milano, S.K, Cerione, R.A. | 登録日 | 2023-05-29 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15, 2024
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8T0Z
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![BU of 8t0z by Molmil](/molmil-images/mine/8t0z) | Human liver-type glutaminase (K253A) with L-Gln, filamentous form | 分子名称: | GLUTAMINE, Glutaminase liver isoform, mitochondrial | 著者 | Feng, S, Aplin, C, Nguyen, T.-T.T, Milano, S.K, Cerione, R.A. | 登録日 | 2023-06-01 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15, 2024
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