4BN4
Structure of human SIRT3 in complex with ADP-ribose
Summary for 4BN4
Entry DOI | 10.2210/pdb4bn4/pdb |
Related | 4BN5 |
Descriptor | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL, ZINC ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase, lysine deacetylase, adp ribose |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion matrix: Q9NTG7 |
Total number of polymer chains | 1 |
Total formula weight | 32428.25 |
Authors | Nguyen, G.T.T.,Schaefer, S.,Gertz, M.,Weyand, M.,Steegborn, C. (deposition date: 2013-05-13, release date: 2013-06-26, Last modification date: 2023-12-20) |
Primary citation | Nguyen, G.T.T.,Schaefer, S.,Gertz, M.,Weyand, M.,Steegborn, C. Structures of Human Sirtuin 3 Complexes with Adp-Ribose and with Carba-Nad+ and Srt1720: Binding Details and Inhibition Mechanism Acta Crystallogr.,Sect.D, 69:1423-, 2013 Cited by PubMed: 23897466DOI: 10.1107/S0907444913015448 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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