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6V4P
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BU of 6v4p by Molmil
Structure of the integrin AlphaIIbBeta3-Abciximab complex
分子名称: Abciximab, heavy chain, light chain, ...
著者Nesic, D, Zhang, Y, Spasic, A, Li, J, Provasi, D, Filizola, M, Walz, T, Coller, B.S.
登録日2019-11-28
公開日2020-02-05
最終更新日2020-03-11
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex.
Arterioscler Thromb Vasc Biol., 40, 2020
1SR4
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BU of 1sr4 by Molmil
Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin
分子名称: BROMIDE ION, Cytolethal distending toxin subunit A, cytolethal distending toxin protein B, ...
著者Nesic, D, Hsu, Y, Stebbins, C.E.
登録日2004-03-22
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Assembly and Function of a Bacterial Genotoxin
Nature, 429, 2004
7LA4
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Integrin AlphaIIbBeta3-PT25-2 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J.
登録日2021-01-05
公開日2022-01-12
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding.
Blood Adv, 5, 2021
3IEC
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BU of 3iec by Molmil
Helicobacter pylori CagA Inhibits PAR1/MARK Family Kinases by Mimicking Host Substrates
分子名称: Cytotoxicity-associated immunodominant antigen, Serine/threonine-protein kinase MARK2
著者Stebbins, C.E, Nesic, D, Miller, M.
登録日2009-07-22
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates.
Nat.Struct.Mol.Biol., 17, 2010
4IRV
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BU of 4irv by Molmil
Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
分子名称: Apoptosis-stimulating of p53 protein 2, Cytotoxicity-associated immunodominant antigen
著者Stebbins, C.E, Nesic, D.
登録日2013-01-15
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
Proc.Natl.Acad.Sci.USA, 111, 2014
6MK0
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BU of 6mk0 by Molmil
Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161
分子名称: (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者van Agthoven, J, Arnaout, M.A.
登録日2018-09-24
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Novel Pure alphaVbeta3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations
Acs Pharmacol Transl Sci, 2, 2019
6ELC
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BU of 6elc by Molmil
Crystal Structure of O-linked Glycosylated VSG3
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stebbins, C.E.
登録日2017-09-28
公開日2018-07-11
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat.
Nat Microbiol, 3, 2018

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件を2024-07-10に公開中

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