6LK2
 
 | | Crystal structure of Providencia alcalifaciens 3-dehydroquinate synthase (DHQS) in complex with Mg2+, NAD and chlorogenic acid | | 分子名称: | (1R,3R,4S,5R)-3-[3-[3,4-bis(oxidanyl)phenyl]propanoyloxy]-1,4,5-tris(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 3-dehydroquinate synthase, ... | | 著者 | Neetu, N, Katiki, M, Kumar, P. | | 登録日 | 2019-12-17 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway.
J.Bacteriol., 202, 2020
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6LLA
 | | Crystal structure of Providencia alcalifaciens 3-dehydroquinate synthase (DHQS) in complex with Mg2+ and NAD | | 分子名称: | 1,2-ETHANEDIOL, 3-dehydroquinate synthase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Neetu, N, Katiki, M, Kumar, P. | | 登録日 | 2019-12-22 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway.
J.Bacteriol., 202, 2020
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8JFV
 | | Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone | | 分子名称: | 1,2-ETHANEDIOL, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Neetu, N, Sharma, M, Mahto, J.K, Kumar, P. | | 登録日 | 2023-05-19 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Sulisobenzone is a potent inhibitor of the global transcription factor Cra.
J.Struct.Biol., 215, 2023
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8JFF
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7DOB
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7DOA
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8ELB
 | | CTX-M-14 beta-lactamase mutant- N132A | | 分子名称: | Beta-lactamase, DI(HYDROXYETHYL)ETHER | | 著者 | Lu, S, Neetu, N, Palzkill, T. | | 登録日 | 2022-09-23 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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7F44
 | | Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with the cofactor NAD | | 分子名称: | CALCIUM ION, Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL, ... | | 著者 | Katiki, M, Neetu, N, Pratap, S, Kumar, P. | | 登録日 | 2021-06-17 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Biochemical and structural basis for Moraxella catarrhalis enoyl-acyl carrier protein reductase (FabI) inhibition by triclosan and estradiol.
Biochimie, 198, 2022
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8DPQ
 | | Beta-lactamase CTX-M-14 N170A | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase | | 著者 | Lu, S, Neetu, N, Palzkill, T. | | 登録日 | 2022-07-15 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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8TL8
 | | Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | | 分子名称: | GLYCOCHOLIC ACID, Protein sigma-NS | | 著者 | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | | 登録日 | 2023-07-26 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories.
Nat Commun, 15, 2024
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7FCM
 | | Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with NAD and Triclosan | | 分子名称: | CALCIUM ION, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Katiki, M, Neetu, N, Pratap, S, Kumar, P. | | 登録日 | 2021-07-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Biochemical and structural basis for Moraxella catarrhalis enoyl-acyl carrier protein reductase (FabI) inhibition by triclosan and estradiol.
Biochimie, 198, 2022
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8TMT
 | | Crystal structure of KPC-44 carbapenemase in complex with vaborbactam | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, LITHIUM ION, ... | | 著者 | Sun, Z, Palzkill, T, Hu, L, Neetu, N, Lin, H, Sankaran, B, Wang, J, Prasad, B. | | 登録日 | 2023-07-30 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
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7FC8
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8ELA
 | | CTX-M-14 beta-lactamase mutant - N132A w MES | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase, CHLORIDE ION, ... | | 著者 | Lu, S, Palzkill, T, Hu, L, Prasad, B.V.V. | | 登録日 | 2022-09-23 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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7V25
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7V28
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8DOD
 | | Beta-lactamase CTX-M-14 S130A | | 分子名称: | Beta-lactamase, POTASSIUM ION | | 著者 | Lu, S, Palzkill, T. | | 登録日 | 2022-07-12 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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8DOE
 | | Crystal Structure of CTX-M-14 N106A | | 分子名称: | Beta-lactamase | | 著者 | Lu, S, Palzkill, T. | | 登録日 | 2022-07-12 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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8DP4
 | | Beta-lactamase CTX-M-14 T235A | | 分子名称: | Beta-lactamase | | 著者 | Lu, S, Palzkill, T. | | 登録日 | 2022-07-14 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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8DON
 | | Beta-lactamase CTX-M-14 T215A | | 分子名称: | Beta-lactamase, PHOSPHATE ION | | 著者 | Lu, S, Palzkill, T. | | 登録日 | 2022-07-13 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance.
J.Biol.Chem., 299, 2023
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7X1X
 | | Crystal Structure of cis-4,5-dihydrodiol phthalate dehydrogenase in complex with NAD+ | | 分子名称: | 4,5-dihydroxyphthalate dehydrogenase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Sharma, M, Mahto, J.K, Kumar, P. | | 登録日 | 2022-02-24 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Conformational flexibility enables catalysis of phthalate cis-4,5-dihydrodiol dehydrogenase.
Arch.Biochem.Biophys., 727, 2022
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7WZD
 | | Crystal Structure of cis-4,5-dihydrodiol phthalate dehydrogenase from Comamonas testosteroni KF1 | | 分子名称: | 4,5-dihydroxyphthalate dehydrogenase, GLYCEROL | | 著者 | Sharma, M, Mahto, J.K, Kumar, P. | | 登録日 | 2022-02-17 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Conformational flexibility enables catalysis of phthalate cis-4,5-dihydrodiol dehydrogenase.
Arch.Biochem.Biophys., 727, 2022
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7X2Y
 | | Crystal Structure of cis-4,5-dihydrodiol phthalate dehydrogenase in complex with NAD+ and 3-Hydroxybenzoate | | 分子名称: | 3-HYDROXYBENZOIC ACID, 4,5-dihydroxyphthalate dehydrogenase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sharma, M, Mahto, J.K, Kumar, P. | | 登録日 | 2022-02-26 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Conformational flexibility enables catalysis of phthalate cis-4,5-dihydrodiol dehydrogenase.
Arch.Biochem.Biophys., 727, 2022
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7VJU
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8TN0
 | | Crystal structure of KPC-44 carbapenemase w/o cryoprotectant | | 分子名称: | SULFATE ION, beta-lactamase | | 著者 | Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. | | 登録日 | 2023-07-31 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
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