8DOE

Crystal Structure of CTX-M-14 N106A

Summary for 8DOE

Entry DOI	10.2210/pdb8doe/pdb
Descriptor	Beta-lactamase (2 entities in total)
Functional Keywords	beta-lactamase, b-lactam antibiotic resistance, mutation, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	27829.39
Authors	Lu, S.,Palzkill, T. (deposition date: 2022-07-12, release date: 2023-04-05, Last modification date: 2023-10-25)
Primary citation	Lu, S.,Montoya, M.,Hu, L.,Neetu, N.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T. Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J.Biol.Chem., 299:104630-104630, 2023 Cited by PubMed: 36963495 DOI: 10.1016/j.jbc.2023.104630 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation