8DON
Beta-lactamase CTX-M-14 T215A
Summary for 8DON
| Entry DOI | 10.2210/pdb8don/pdb |
| Descriptor | Beta-lactamase, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | beta-lactamase, antibiotic resistance, beta-lactam, ctx-m-14, hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 27937.36 |
| Authors | Lu, S.,Palzkill, T. (deposition date: 2022-07-13, release date: 2023-04-05, Last modification date: 2023-10-25) |
| Primary citation | Lu, S.,Montoya, M.,Hu, L.,Neetu, N.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T. Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J.Biol.Chem., 299:104630-104630, 2023 Cited by PubMed: 36963495DOI: 10.1016/j.jbc.2023.104630 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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