7FCM

Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with NAD and Triclosan

Summary for 7FCM

Entry DOI	10.2210/pdb7fcm/pdb
Descriptor	Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (5 entities in total)
Functional Keywords	fabi, nadh, triclosan, oxidoreductase
Biological source	Moraxella catarrhalis (strain BBH18)
Total number of polymer chains	2
Total formula weight	63674.03
Authors	Katiki, M.,Neetu, N.,Pratap, S.,Kumar, P. (deposition date: 2021-07-15, release date: 2022-07-20, Last modification date: 2024-01-31)
Primary citation	Katiki, M.,Neetu, N.,Pratap, S.,Kumar, P. Biochemical and structural basis for Moraxella catarrhalis enoyl-acyl carrier protein reductase (FabI) inhibition by triclosan and estradiol. Biochimie, 198:8-22, 2022 Cited by PubMed: 35276316 DOI: 10.1016/j.biochi.2022.02.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation