7FCM

Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with NAD and Triclosan

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	287	30864.0	2	UniProt (D5VCE0)	Moraxella catarrhalis (strain BBH18)
2	C, F (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, G (A, B)	TRICLOSAN	non-polymer		289.5	2	Chemie (TCL)
4	E (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
5	H, I (A, B)	water	water		18.0	185	Chemie (HOH)

Sequence modifications

A, B: 1 - 274 (UniProt: D5VCE0)

PDB	External Database	Details
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag
Gln 222	Gly 222	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61728.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1946.0
All*	Total formula weight	63674.0

*Water molecules are not included.