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7FCM

Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with NAD and Triclosan

Functional Information from GO Data
ChainGOidnamespacecontents
A0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
A0006633biological_processfatty acid biosynthetic process
B0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
B0006633biological_processfatty acid biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues28
Detailsbinding site for residue NAD A 301
ChainResidue
AGLY12
AALA95
AILE96
AGLY97
ALEU149
ATHR150
ALYS168
AALA194
AGLY195
APRO196
AILE197
AILE13
ATHR199
ALEU200
AALA201
ATCL302
AHOH405
AHOH424
AHOH438
AHOH439
AHOH441
AALA14
ASER18
AILE19
APRO39
ACYS62
AASP63
AVAL64

site_idAC2
Number of Residues9
Detailsbinding site for residue TCL A 302
ChainResidue
AGLY97
AALA99
ALEU104
ATYR151
ATYR161
AALA201
AALA202
AMET211
ANAD301

site_idAC3
Number of Residues6
Detailsbinding site for residue CA A 303
ChainResidue
AGLU248
AILE249
BGLU248
BILE249
BHOH476
BHOH478

site_idAC4
Number of Residues28
Detailsbinding site for residue NAD B 301
ChainResidue
BGLY12
BILE13
BALA14
BSER18
BILE19
BPRO39
BILE43
BCYS62
BASP63
BVAL64
BALA95
BILE96
BGLY97
BLEU149
BTHR150
BLYS168
BALA194
BGLY195
BPRO196
BILE197
BTHR199
BALA201
BTCL302
BHOH402
BHOH438
BHOH439
BHOH443
BHOH447

site_idAC5
Number of Residues7
Detailsbinding site for residue TCL B 302
ChainResidue
BGLY97
BALA99
BLEU104
BTYR151
BTYR161
BALA201
BNAD301

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PDB entries from 2024-10-30

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