4LL9
 
 | | Crystal structure of D3D4 domain of the LILRB1 molecule | | 分子名称: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | | 著者 | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2013-07-09 | | 公開日 | 2013-09-11 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | | 主引用文献 | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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4LLA
 | | Crystal structure of D3D4 domain of the LILRB2 molecule | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 2 | | 著者 | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2013-07-09 | | 公開日 | 2013-09-11 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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2GC8
 | | Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase | | 分子名称: | 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE, RNA-directed RNA polymerase | | 著者 | Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, K.J, Sukits, S.F, Svenson, K, Bard, J, Ellingboe, J.W, Agarwal, A, Krishnamurthy, G, Howe, A.Y, Orlowski, M, Feld, B, O'connell, J, Mansour, T.S. | | 登録日 | 2006-03-13 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site.
J.Med.Chem., 49, 2006
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3P2T
 | | Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 4, SULFATE ION | | 著者 | Chen, Y, Nam, G, Cheng, H, Zhang, J.H, Willcox, B.E, Gao, G.F. | | 登録日 | 2010-10-04 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance
J.Biol.Chem., 286, 2011
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5LKN
 | | NMR solution structure of human FNIII domain 2 of NCAM | | 分子名称: | Neural cell adhesion molecule 1 | | 著者 | Slapsak, U, Salzano, G, Amin, L, Abskharon, R.N.N, Ilc, G, Zupancic, B, Biljan, I, Plavec, J, Giachin, G, Legname, G. | | 登録日 | 2016-07-22 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain.
J.Biol.Chem., 291, 2016
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2LFT
 | | Human prion protein with E219K protective polymorphism | | 分子名称: | Major prion protein | | 著者 | Biljan, I, Ilc, G, Giacin, G, Zhukov, I, Plavec, J, Legname, G. | | 登録日 | 2011-07-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism.
Biochem.J., 446, 2012
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2LSB
 | | Solution-state NMR structure of the human prion protein | | 分子名称: | Major prion protein | | 著者 | Biljan, I, Ilc, G, Giancin, G, Zhukov, I, Plavec, J, Legname, G. | | 登録日 | 2012-04-26 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism.
Biochem.J., 446, 2012
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2LV1
 | | Solution-state NMR structure of prion protein mutant V210I at neutral pH | | 分子名称: | Major prion protein | | 著者 | Biljan, I, Ilc, G, Giachin, G, Legname, G, Plavec, J. | | 登録日 | 2012-06-26 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Rearrangements at Physiological pH: Nuclear Magnetic Resonance Insights from the V210I Human Prion Protein Mutant.
Biochemistry, 51, 2012
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2KUN
 | | Three dimensional structure of HuPrP(90-231 M129 Q212P) | | 分子名称: | Major prion protein | | 著者 | Ilc, G, Giachin, G, Jaremko, M, Jaremko, L, Zhukov, I, Plavec, J, Legname, G, Benetti, F. | | 登録日 | 2010-02-23 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features.
Plos One, 5, 2010
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2LEJ
 | | human prion protein mutant HuPrP(90-231, M129, V210I) | | 分子名称: | Major prion protein | | 著者 | Biljan, I, Ilc, G, Giachin, G, Raspadori, A, Zhukov, I, Plavec, J, Legname, G. | | 登録日 | 2011-06-16 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Toward the Molecular Basis of Inherited Prion Diseases: NMR Structure of the Human Prion Protein with V210I Mutation.
J.Mol.Biol., 412, 2011
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4KML
 | | Probing the N-terminal beta-sheet conversion in the crystal structure of the full-length human prion protein bound to a Nanobody | | 分子名称: | Major prion protein, Nanobody | | 著者 | Abskharon, R.N.N, Giachin, G, Wohlkonig, A, Soror, S.H, Pardon, E, Legname, G, Steyaert, J. | | 登録日 | 2013-05-08 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Probing the N-Terminal beta-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody.
J.Am.Chem.Soc., 136, 2014
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4N9O
 | | Probing the N-terminal beta-sheet conversion in the crystal structure of the human prion protein bound to a Nanobody | | 分子名称: | Major prion protein, Nanobody Nb484 | | 著者 | Abskharon, R.N.N, Giachin, G, Wohlkonig, A, Soror, S.H, Pardon, E, Legname, G, Steyaert, J. | | 登録日 | 2013-10-21 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Probing the N-Terminal beta-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody.
J.Am.Chem.Soc., 136, 2014
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6AEE
 | | Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G | | 分子名称: | 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Wang, Q, Song, H, Qi, J, Gao, G.F. | | 登録日 | 2018-08-04 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.303 Å) | | 主引用文献 | Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex.
Cell. Mol. Immunol., 2019
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6AED
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3Q2C
 | | Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e) | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily A member 3 | | 著者 | Ryu, M, Chen, Y, Qi, J.X, Liu, J, Shi, Y, Cheng, H, Gao, G.F. | | 登録日 | 2010-12-20 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence
Plos One, 6, 2011
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3F5P
 | | Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor | | 分子名称: | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile, Insulin-like growth factor 1 receptor | | 著者 | Xu, W, Miller, L.M, Mayer, S.C, Berger, D.M, Boschelli, D.H, Boschelli, F. | | 登録日 | 2008-11-04 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Bioorg.Med.Chem.Lett., 19, 2009
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6HEQ
 | | Prion nanobody 484 | | 分子名称: | Prion nanobody 484 | | 著者 | Soror, S.H, Abskharon, R.N, Wohlkonig, A. | | 登録日 | 2018-08-20 | | 公開日 | 2019-12-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
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471D
 | | CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3') | | 著者 | Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M. | | 登録日 | 1999-04-29 | | 公開日 | 1999-05-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
Nat.Struct.Biol., 6, 1999
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469D
 | | CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3') | | 著者 | Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M. | | 登録日 | 1999-04-29 | | 公開日 | 1999-05-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
Nat.Struct.Biol., 6, 1999
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468D
 | | CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3') | | 著者 | Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M. | | 登録日 | 1999-04-29 | | 公開日 | 1999-05-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
Nat.Struct.Biol., 6, 1999
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470D
 | | CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3') | | 著者 | Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M. | | 登録日 | 1999-04-29 | | 公開日 | 1999-05-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
Nat.Struct.Biol., 6, 1999
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6HHD
 | | Mouse Prion Protein in complex with Nanobody 484 | | 分子名称: | CHLORIDE ION, GLYCEROL, Major prion protein, ... | | 著者 | Soror, S, Abskharon, R, Wohlkonig, A. | | 登録日 | 2018-08-28 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
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6HER
 | | Mouse prion protein in complex with Nanobody 484 | | 分子名称: | GLYCEROL, Major prion protein, Nanobody 484, ... | | 著者 | Soror, S.H, Abskharon, R, Wohlkonig, A. | | 登録日 | 2018-08-20 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.199 Å) | | 主引用文献 | Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
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2R7B
 | | Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor | | 分子名称: | 10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine, 3-phosphoinositide-dependent protein kinase 1, SULFATE ION | | 著者 | Olland, A.M. | | 登録日 | 2007-09-07 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of Dibenzo[c,f][2,7]naphthyridines as Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 Inhibitors.
J.Med.Chem., 50, 2007
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8OM2
 | | Small subunit of yeast mitochondrial ribosome in complex with METTL17/Rsm22. | | 分子名称: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | | 著者 | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | | 登録日 | 2023-03-31 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Mol.Cell, 84, 2024
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