6HER

Mouse prion protein in complex with Nanobody 484

Summary for 6HER

• Entry DOI: 10.2210/pdb6her/pdb
• Descriptor: Major prion protein, Nanobody 484, SULFATE ION, ... (5 entities in total)
• Functional Keywords: prion, nanobody, aggregation, b-sheet, protein binding
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 26803.61

Authors

Soror, S.H.,Abskharon, R.,Wohlkonig, A. (deposition date: 2018-08-20, release date: 2019-12-04, Last modification date: 2024-01-17)

• Primary citation: Abskharon, R.,Wang, F.,Wohlkonig, A.,Ruan, J.,Soror, S.,Giachin, G.,Pardon, E.,Zou, W.,Legname, G.,Ma, J.,Steyaert, J.; Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.; Plos Pathog., 15:e1008139-e1008139, 2019; PubMed: 31815959; DOI: 10.1371/journal.ppat.1008139

Experimental method

X-RAY DIFFRACTION (1.199 Å)