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1MIL
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TRANSFORMING PROTEIN
分子名称: SHC ADAPTOR PROTEIN
著者Mikol, V.
登録日1995-09-20
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data.
J.Mol.Biol., 254, 1995
1MIK
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THE ROLE OF WATER MOLECULES IN THE STRUCTURE-BASED DESIGN OF (5-HYDROXYNORVALINE)-2-CYCLOSPORIN: SYNTHESIS, BIOLOGICAL ACTIVITY, AND CRYSTALLOGRAPHIC ANALYSIS WITH CYCLOPHILIN A
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V.
登録日1995-09-20
公開日1996-03-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The Role of Water Molecules in the Structure-Based Design of (5-Hydroxynorvaline)-2-Cyclosporin: Synthesis, Biological Activity, and Crystallographic Analysis with Cyclophilin A.
J.Med.Chem., 38, 1995
1CWB
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THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Walkinshaw, M.D.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The X-Ray Structure of (Mebm2T)1-Cyclosporin Complexed with Cyclophilin a Provides an Explanation for its Anomalously High Immunosuppressive Activity.
Protein Eng., 7, 1994
1CWA
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X-RAY STRUCTURE OF A MONOMERIC CYCLOPHILIN A-CYCLOSPORIN A CRYSTAL COMPLEX AT 2.1 ANGSTROMS RESOLUTION
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Walkinshaw, M.D.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Structure of a Monomeric Cyclophilin A-Cyclosporin a Crystal Complex at 2.1 A Resolution.
J.Mol.Biol., 234, 1993
1CYN
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CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B
著者Mikol, V, Kallen, J, Walkinshaw, M.D.
登録日1995-05-22
公開日1996-01-29
最終更新日2018-09-12
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain.
Proc.Natl.Acad.Sci.USA, 91, 1994
1A33
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PEPTIDYLPROLYL ISOMERASE, CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI
分子名称: PEPTIDYLPROLYL ISOMERASE
著者Mikol, V, Ma, D, Carlow, C.K.S.
登録日1998-01-27
公開日1998-07-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the cyclophilin-like domain from the parasitic nematode Brugia malayi.
Protein Sci., 7, 1998
1MIM
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IGG FAB FRAGMENT (CD25-BINDING)
分子名称: CHIMERIC SDZ CHI621
著者Mikol, V.
登録日1995-12-04
公開日1997-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the fab fragment of SDZ CHI621: a chimeric antibody against CD25.
Acta Crystallogr.,Sect.D, 52, 1996
1CWO
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HUMAN CYCLOPHILIN A COMPLEXED WITH THR2, LEU5, D-HIV8, LEU10 CYCLOSPORIN
分子名称: CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-06-05
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Conformational Differences of an Immunosuppressant Peptolide in a Single Crystal and in a Crystal Complex with Human Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWD
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HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE
分子名称: (PHOSPHONOMETHYL)PHENYLALANINE-CONTAINING PEPTIDE PRO-GLU-GLY-ASP-PM3-GLU-GLU-VAL-LEU, P56LCK TYROSINE KINASE
著者Mikol, V.
登録日1995-09-06
公開日1996-12-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The crystal structures of the SH2 domain of p56lck complexed with two phosphopeptides suggest a gated peptide binding site.
J.Mol.Biol., 246, 1995
1CWE
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HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE
分子名称: P56LCK TYROSINE KINASE, PHOSPHOPEPTIDE ACQ-PMP-GLU-GLU-ILE-PRO
著者Mikol, V.
登録日1995-09-06
公開日1996-12-07
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structures of the SH2 domain of p56lck complexed with two phosphopeptides suggest a gated peptide binding site.
J.Mol.Biol., 246, 1995
1CWC
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IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Improved Binding Affinity for Cyclophilin a by a Cyclosporin Derivative Singly Modified at its Effector Domain.
J.Med.Chem., 37, 1994
1LQW
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Crystal Structure of S.aureus Peptide Deformylase
分子名称: PEPTIDE DEFORMYLASE PDF1, ZINC ION
著者Mikol, V.
登録日2002-05-14
公開日2002-07-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
J.Mol.Biol., 320, 2002
1BCK
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN
分子名称: CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-04-30
公開日1998-09-16
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWH
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HUMAN CYCLOPHILIN A COMPLEXED WITH 3-D-SER CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-07
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWJ
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN
分子名称: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-25
公開日1998-08-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWM
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-26
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWI
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN
分子名称: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-25
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWL
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-26
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWK
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HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN
分子名称: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-26
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWF
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN
分子名称: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-04-30
公開日1998-07-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
4CP6
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The Crystal structure of Pneumococcal vaccine antigen PcpA
分子名称: CHOLINE BINDING PROTEIN PCPA
著者Vallee, F, Steier, V, Oloo, E, Chawla, D, Vonrhein, C, Steinmetz, A, Mathieu, M, Rak, A, Mikol, V, Oomen, R.
登録日2014-01-31
公開日2015-02-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献The Crystal Structure of Pneumoccocal Vaccine Antigen Pcpa
To be Published
4UUQ
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Crystal structure of human mono-glyceride lipase in complex with SAR127303
分子名称: 4-({[(4-chlorophenyl)sulfonyl]amino}methyl)piperidine-1-carboxylic acid, MONOGLYCERIDE LIPASE
著者Griebel, G, Pichat, P, Beeske, S, Leroy, T, Redon, N, Francon, D, Bert, L, Even, L, Lopez-Grancha, M, Tolstykh, T, Sun, F, Yu, Q, Brittain, S, Arlt, H, He, T, Zhang, B, Wiederschain, D, Bertrand, T, Houtman, J, Rak, A, Vallee, F, Michot, N, Auge, F, Menet, V, Bergis, O.E, George, P, Avenet, P, Mikol, V, Didier, M, Escoubet, J.
登録日2014-07-30
公開日2015-01-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Selective Blockade of the Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol Impairs Learning and Memory Performance While Producing Antinociceptive Activity in Rodents.
Sci.Rep., 5, 2015
1W78
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E.coli FolC in complex with DHPP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, FOLC BIFUNCTIONAL PROTEIN, MAGNESIUM ION, ...
著者Mathieu, M, Debousker, G, Vincent, S, Viviani, F, Bamas-Jacques, N, Mikol, V.
登録日2004-08-31
公開日2005-02-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Escherichia Coli Folc Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-Microbial Therapy
J.Biol.Chem., 280, 2005
1W7K
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E.coli FolC in complex with ADP, without folate substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, FOLC BIFUNCTIONAL PROTEIN, MAGNESIUM ION, ...
著者Mathieu, M, Debousker, G, Vincent, S, Viviani, F, Bamas-Jacques, N, Mikol, V.
登録日2004-09-06
公開日2005-02-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Escherichia Coli Folc Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-Microbial Therapy
J.Biol.Chem., 280, 2005
1LRU
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Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin
分子名称: ACTINONIN, PEPTIDE DEFORMYLASE, SULFATE ION, ...
著者Guilloteau, J.-P, Mathieu, M, Giglione, C, Blanc, V, Dupuy, A, Chevrier, M, Gil, P, Famechon, A, Meinnel, T, Mikol, V.
登録日2002-05-16
公開日2002-07-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
J.Mol.Biol., 320, 2002

 

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