4RE6
 
 | | Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor | | 分子名称: | Acylamino-acid-releasing enzyme, CHLORIDE ION, N-[(benzyloxy)carbonyl]glycyl-N-[(2S,3R)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]glycinamide | | 著者 | Menyhard, D.K, Orgovan, Z, Szeltner, Z, Szamosi, I, Harmat, V. | | 登録日 | 2014-09-22 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.
Acta Crystallogr.,Sect.D, 71, 2015
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4RE5
 | | Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Acylamino-acid-releasing enzyme, ... | | 著者 | Menyhard, D.K, Orgovan, Z, Szeltner, Z, Szamosi, I, Harmat, V. | | 登録日 | 2014-09-22 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.
Acta Crystallogr.,Sect.D, 71, 2015
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4HXF
 | | Acylaminoacyl peptidase in complex with Z-Gly-Gly-Phe-chloromethyl ketone | | 分子名称: | CHLORIDE ION, HEXANE-1,6-DIOL, MAGNESIUM ION, ... | | 著者 | Kiss-Szeman, A, Menyhard, D.K, Tichy-Racs, E, Hornung, B, Radi, K, Szeltner, Z, Domokos, K, Szamosi, I, Naray-Szabo, G, Polgar, L, Harmat, V. | | 登録日 | 2012-11-09 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
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4HXE
 | | Pyrococcus horikoshii acylaminoacyl peptidase (uncomplexed) | | 分子名称: | HEXANE-1,6-DIOL, MAGNESIUM ION, Putative uncharacterized protein PH0594 | | 著者 | Tichy-Racs, E, Hornung, B, Radi, K, Menyhard, D.K, Kiss-Szeman, A, Szeltner, Z, Domokos, K, Szamosi, I, Naray-Szabo, G, Polgar, L, Harmat, V. | | 登録日 | 2012-11-09 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
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4HXG
 | | Pyrococcus horikoshii acylaminoacyl peptidase (orthorhombic crystal form) | | 分子名称: | CHLORIDE ION, HEXANE-1,6-DIOL, MAGNESIUM ION, ... | | 著者 | Kiss-Szeman, A, Menyhard, D.K, Tichy-Racs, E, Hornung, B, Radi, K, Szeltner, Z, Domokos, K, Szamosi, I, Naray-Szabo, G, Polgar, L, Harmat, V. | | 登録日 | 2012-11-09 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
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7PX8
 | | CryoEM structure of mammalian acylaminoacyl-peptidase | | 分子名称: | Acylamino-acid-releasing enzyme | | 著者 | Kiss-Szeman, A.J, Harmat, V, Menyhard, D.K, Straner, P, Jakli, I, Hosogi, N, Perczel, A. | | 登録日 | 2021-10-08 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad.
Chem Sci, 13, 2022
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3O4J
 | | Structure and Catalysis of Acylaminoacyl Peptidase | | 分子名称: | Acylamino-acid-releasing enzyme, CHLORIDE ION, GLYCEROL, ... | | 著者 | Harmat, V, Domokos, K, Menyhard, D.K, Pallo, A, Szeltner, Z, Szamosi, I, Beke-Somfai, T, Naray-Szabo, G, Polgar, L. | | 登録日 | 2010-07-27 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
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3O4I
 | | Structure and Catalysis of Acylaminoacyl Peptidase | | 分子名称: | Acylamino-acid-releasing enzyme, CHLORIDE ION, GLYCEROL | | 著者 | Harmat, V, Domokos, K, Menyhard, D.K, Pallo, A, Szeltner, Z, Szamosi, I, Beke-Somfai, T, Naray-Szabo, G, Polgar, L. | | 登録日 | 2010-07-27 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
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3O4H
 | | Structure and Catalysis of Acylaminoacyl Peptidase | | 分子名称: | Acylamino-acid-releasing enzyme, GLYCEROL, SODIUM ION | | 著者 | Harmat, V, Domokos, K, Menyhard, D.K, Pallo, A, Szeltner, Z, Szamosi, I, Beke-Somfai, T, Naray-Szabo, G, Polgar, L. | | 登録日 | 2010-07-27 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
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3O4G
 | | Structure and Catalysis of Acylaminoacyl Peptidase | | 分子名称: | Acylamino-acid-releasing enzyme, GLYCEROL | | 著者 | Harmat, V, Domokos, K, Menyhard, D.K, Pallo, A, Szeltner, Z, Szamosi, I, Beke-Somfai, T, Naray-Szabo, G, Polgar, L. | | 登録日 | 2010-07-27 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
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7QUN
 | | CryoEM structure of mammalian AAP in complex with Meropenem | | 分子名称: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Acylamino-acid-releasing enzyme | | 著者 | Kiss-Szeman, A.J, Harmat, V, Straner, P, Jakli, I, Menyhard, K.D, Masiulis, S, Perczel, A. | | 登録日 | 2022-01-18 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase-meropenem complex.
Chem Sci, 13, 2022
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7ARX
 | | Crystal structure of the catalytic fragment of masp-1 in complex with SFMI1 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Mannan-binding lectin serine protease 1, SFMI1 - Sunflower MASP1 inhibitor | | 著者 | Durvanger, Z, Harmat, V, Dobo, J, Megyeri, M. | | 登録日 | 2020-10-26 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides.
Acs Chem.Biol., 17, 2022
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