2QD1
 
 | | 2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2007-06-20 | | 公開日 | 2007-10-30 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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2QD2
 | | F110A variant of human ferrochelatase with protoheme bound | | 分子名称: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilota, W.N. | | 登録日 | 2007-06-20 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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2QD4
 | | Wild type human ferrochelatase crystallized with MnCl2 | | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2007-06-20 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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2QD3
 | | Wild type human ferrochelatase crystallized with ammonium sulfate | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2007-06-20 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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3HCR
 | | Human Ferrochelatase with deuteroporphyrin and Ni Bound | | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, ... | | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2009-05-06 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCO
 | | Human ferrochelatase with Cd and protoporphyrin IX bound | | 分子名称: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2009-05-06 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCN
 | | Hg and protoporphyrin bound Human Ferrochelatase | | 分子名称: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2009-05-06 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCP
 | | Human ferrochelatase with Mn and deuteroporphyrin bound | | 分子名称: | CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2009-05-06 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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4F4D
 | | F337R variant of human ferrochelatase | | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A. | | 登録日 | 2012-05-10 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | F337R Variant of Human Ferrochelatase
TO BE PUBLISHED
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3AQI
 | | H240A variant of human ferrochelatase | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A. | | 登録日 | 2010-11-03 | | 公開日 | 2012-01-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | H240A variant of human ferrochelatase
To be published
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4MK4
 | | S197C variant of human ferrochelatase. | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A. | | 登録日 | 2013-09-04 | | 公開日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | S197C variant of human ferrochelatase.
To be Published
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2PNJ
 | | Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P. | | 登録日 | 2007-04-24 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis
Biochemistry, 46, 2007
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2PO5
 | | Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, A.E.W, Burden, A, Dailey, T.A, Rose, J.P. | | 登録日 | 2007-04-25 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis
Biochemistry, 46, 2007
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2PO7
 | | Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A, Dailey, T.A, Rose, J.P. | | 登録日 | 2007-04-25 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis.
Biochemistry, 46, 2007
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7L78
 | | H235C variant of Yeast Ferrochelatase | | 分子名称: | CHOLIC ACID, Ferrochelatase, mitochondrial | | 著者 | Lanzilotta, W.N, Medlock, A.E. | | 登録日 | 2020-12-27 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Redox Biol, 46, 2021
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4KLC
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4KLA
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4KLR
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4KMM
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2QD5
 | | Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound | | 分子名称: | ACETIC ACID, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Meldock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | 登録日 | 2007-06-20 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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