1G84
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![BU of 1g84 by Molmil](/molmil-images/mine/1g84) | THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE | 分子名称: | IMMUNOGLOBULIN E | 著者 | McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J. | 登録日 | 2000-11-16 | 公開日 | 2001-05-16 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha. Nat.Struct.Biol., 8, 2001
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1XBH
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![BU of 1xbh by Molmil](/molmil-images/mine/1xbh) | A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262) | 分子名称: | PROTEIN (CYCLO(L-262)) | 著者 | Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D. | 登録日 | 1999-02-17 | 公開日 | 1999-02-21 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer J.Am.Chem.Soc., 119, 1997
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1C4B
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![BU of 1c4b by Molmil](/molmil-images/mine/1c4b) | A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(RD-262) | 分子名称: | PROTEIN (CYCLO(RD-262)) | 著者 | Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D. | 登録日 | 1999-08-02 | 公開日 | 1999-08-25 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer J.Am.Chem.Soc., 119, 1997
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1A6S
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![BU of 1a6s by Molmil](/molmil-images/mine/1a6s) | M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES | 分子名称: | GAG POLYPROTEIN | 著者 | Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D. | 登録日 | 1998-03-02 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus J.Mol.Biol., 279, 1998
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1DDB
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![BU of 1ddb by Molmil](/molmil-images/mine/1ddb) | STRUCTURE OF MOUSE BID, NMR, 20 STRUCTURES | 分子名称: | PROTEIN (BID) | 著者 | Mcdonnell, J.M, Fushman, D, Milliman, C, Korsmeyer, S.J, Cowburn, D. | 登録日 | 1999-02-19 | 公開日 | 1999-08-30 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. Cell(Cambridge,Mass.), 96, 1999
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2BOU
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![BU of 2bou by Molmil](/molmil-images/mine/2bou) | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium. | 分子名称: | BARIUM ION, CACODYLATE ION, CALCIUM ION, ... | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-14 | 公開日 | 2006-10-18 | 最終更新日 | 2017-01-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
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2BOX
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![BU of 2box by Molmil](/molmil-images/mine/2box) | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium. | 分子名称: | CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ... | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-14 | 公開日 | 2006-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
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2BO2
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![BU of 2bo2 by Molmil](/molmil-images/mine/2bo2) | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium. | 分子名称: | CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | 登録日 | 2005-04-07 | 公開日 | 2006-08-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55. J.Biol.Chem., 282, 2007
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5G64
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![BU of 5g64 by Molmil](/molmil-images/mine/5g64) | The complex between human IgE-Fc and two anti-IgE Fab fragments | 分子名称: | FAB FRAGMENT, IG EPSILON CHAIN C REGION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Davies, A.M, Allan, E.G, Keeble, A.H, Delgado, J, Cossins, B.P, Mitropoulou, A.N, Pang, M.O.Y, Ceska, T, Beavil, A.J, Craggs, G, Westwood, M, Henry, A.J, McDonnell, J.M, Sutton, B.J. | 登録日 | 2016-06-14 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.715 Å) | 主引用文献 | Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab. J. Biol. Chem., 292, 2017
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8OJT
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![BU of 8ojt by Molmil](/molmil-images/mine/8ojt) | Crystal structure of the human IgD Fab - structure Fab2 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AZIDE ION, ... | 著者 | Davies, A.M, Beavil, R.L, McDonnell, J.M. | 登録日 | 2023-03-24 | 公開日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity. Mol.Immunol., 159, 2023
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8OJS
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![BU of 8ojs by Molmil](/molmil-images/mine/8ojs) | Crystal structure of the human IgD Fab - structure Fab1 | 分子名称: | 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ... | 著者 | Davies, A.M, Beavil, R.L, McDonnell, J.M. | 登録日 | 2023-03-24 | 公開日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity. Mol.Immunol., 159, 2023
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8OJU
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![BU of 8oju by Molmil](/molmil-images/mine/8oju) | Crystal structure of the human IgD Fab - structure Fab3 | 分子名称: | 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ... | 著者 | Davies, A.M, Beavil, R.L, McDonnell, J.M. | 登録日 | 2023-03-24 | 公開日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity. Mol.Immunol., 159, 2023
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8OJV
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![BU of 8ojv by Molmil](/molmil-images/mine/8ojv) | Crystal structure of the human IgD Fab - structure Fab4 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Davies, A.M, Beavil, R.L, McDonnell, J.M. | 登録日 | 2023-03-24 | 公開日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity. Mol.Immunol., 159, 2023
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6Y0L
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![BU of 6y0l by Molmil](/molmil-images/mine/6y0l) | Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N, R253G, S254G mutant | 分子名称: | GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, SULFATE ION | 著者 | Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M. | 登録日 | 2020-02-09 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23. Febs Open Bio, 11, 2021
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6Y0M
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![BU of 6y0m by Molmil](/molmil-images/mine/6y0m) | Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N mutant | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | 著者 | Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M. | 登録日 | 2020-02-09 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23. Febs Open Bio, 11, 2021
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4B53
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![BU of 4b53 by Molmil](/molmil-images/mine/4b53) | Crystal structure of the isolated IgG4 CH3 domain | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Davies, A.M, Rispens, T, den Bleker, T.H, McDonnell, J.M, Gould, H.J, Aalberse, R.C, Sutton, B.J. | 登録日 | 2012-08-02 | 公開日 | 2012-12-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Human Igg4 C(H)3 Dimer Reveals the Role of Arg409 in the Mechanism of Fab-Arm Exchange. Mol.Immunol., 54, 2012
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8Q6K
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![BU of 8q6k by Molmil](/molmil-images/mine/8q6k) | Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ... | 著者 | Davies, A.M, Vester, S.K, McDonnell, J.M. | 登録日 | 2023-08-11 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor. Antibodies, 12, 2023
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6EYO
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![BU of 6eyo by Molmil](/molmil-images/mine/6eyo) | Structure of extended IgE-Fc in complex with two anti-IgE Fabs | 分子名称: | 8D6 Fab heavy chain, 8D6 Fab light chain, Immunoglobulin heavy constant epsilon, ... | 著者 | Chen, J.B, Ramadani, F, Pang, M.O.Y, Beavil, R.L, Holdom, M.D, Mitropoulou, A.N, Beavil, A.J, Gould, H.J, Chang, T.W, Sutton, B.J, McDonnell, J.M, Davies, A.M. | 登録日 | 2017-11-13 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody. Sci Rep, 8, 2018
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6EYN
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![BU of 6eyn by Molmil](/molmil-images/mine/6eyn) | Structure of the 8D6 (anti-IgE) Fab | 分子名称: | 1,2-ETHANEDIOL, 8D6 Fab heavy chain, 8D6 Fab light chain, ... | 著者 | Chen, J.B, Ramadani, F, Pang, M.O.Y, Beavil, R.L, Holdom, M.D, Mitropoulou, A.N, Beavil, A.J, Gould, H.J, Chang, T.W, Sutton, B.J, McDonnell, J.M, Davies, A.M. | 登録日 | 2017-11-13 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody. Sci Rep, 8, 2018
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5O9K
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![BU of 5o9k by Molmil](/molmil-images/mine/5o9k) | Crystal structure of Murine Histmaine-Releasing Factor (HRF/TCTP) | 分子名称: | GLYCEROL, Translationally-controlled tumor protein | 著者 | Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M. | 登録日 | 2017-06-19 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4.014 Å) | 主引用文献 | Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation. Mol. Immunol., 93, 2017
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5O9M
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![BU of 5o9m by Molmil](/molmil-images/mine/5o9m) | Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)containing a disulphide-linked dimer | 分子名称: | DI(HYDROXYETHYL)ETHER, Translationally-controlled tumor protein | 著者 | Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M. | 登録日 | 2017-06-19 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation. Mol. Immunol., 93, 2017
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5O9L
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![BU of 5o9l by Molmil](/molmil-images/mine/5o9l) | Crystal structure of human Histamine-Releasing Factor (HRF/TCTP) | 分子名称: | Translationally-controlled tumor protein | 著者 | Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M. | 登録日 | 2017-06-19 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation. Mol. Immunol., 93, 2017
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1T8D
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![BU of 1t8d by Molmil](/molmil-images/mine/1t8d) | Structure of the C-type lectin domain of CD23 | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor | 著者 | Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M. | 登録日 | 2004-05-12 | 公開日 | 2005-07-26 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of human CD23 and its interactions with IgE and CD21 J.Exp.Med., 202, 2005
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1T8C
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![BU of 1t8c by Molmil](/molmil-images/mine/1t8c) | Structure of the C-type lectin domain of CD23 | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor | 著者 | Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M. | 登録日 | 2004-05-12 | 公開日 | 2005-07-26 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of human CD23 and its interactions with IgE and CD21 J.Exp.Med., 202, 2005
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5MOI
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![BU of 5moi by Molmil](/molmil-images/mine/5moi) | Crystal structure of human IgE-Fc epsilon 3-4 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ig epsilon chain C region, ... | 著者 | Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | 登録日 | 2016-12-14 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E. Biochim. Biophys. Acta, 1865, 2017
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