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2PIS
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BU of 2pis by Molmil
Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs
分子名称: DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E.
登録日2007-04-13
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
J.Am.Chem.Soc., 129, 2007
1IFA
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BU of 1ifa by Molmil
THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA
分子名称: ASPARAGINE, INTERFERON-BETA
著者Mitsui, Y, Senda, T, Matsuda, S, Kawano, G, Nakamura, K.T, Shimizu, H.
登録日1991-10-29
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-dimensional crystal structure of recombinant murine interferon-beta.
EMBO J., 11, 1992
5H03
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BU of 5h03 by Molmil
Crystal structure of an ADP-ribosylating toxin BECa from C. perfringens
分子名称: Binary enterotoxin of Clostridium perfringens component a
著者Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S.
登録日2016-10-03
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens.
Biochem.Biophys.Res.Commun., 480, 2016
5H04
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BU of 5h04 by Molmil
Crystal structure of an ADP-ribosylating toxin BECa of a novel binary enterotoxin of C. perfringens with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a
著者Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S.
登録日2016-10-03
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.825 Å)
主引用文献Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens.
Biochem.Biophys.Res.Commun., 480, 2016
7W64
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BU of 7w64 by Molmil
Crystal structure of minor pilin TcpB from Vibrio cholerae complexed with N-terminal peptide fragment of TcpF
分子名称: CALCIUM ION, CHLORIDE ION, PENTAETHYLENE GLYCOL, ...
著者Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S.
登録日2021-12-01
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor.
Sci Adv, 8, 2022
7W65
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BU of 7w65 by Molmil
Crystal structure of minor pilin TcpB from Vibrio cholerae complexed with secreted protein TcpF
分子名称: Toxin coregulated pilus biosynthesis protein F, Toxin-coregulated pilus biosynthesis protein B
著者Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S.
登録日2021-12-01
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor.
Sci Adv, 8, 2022
7W63
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Crystal structure of minor pilin TcpB from Vibrio cholerae
分子名称: SULFATE ION, Toxin-coregulated pilus biosynthesis protein B
著者Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S.
登録日2021-12-01
公開日2022-11-09
最終更新日2022-11-16
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor.
Sci Adv, 8, 2022
6FP7
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BU of 6fp7 by Molmil
mTFP1/DARPin 1238_E11 complex in space group P6522
分子名称: DARPin1238_E11, GFP-like fluorescent chromoprotein cFP484, GLYCEROL
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FPA
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BU of 6fpa by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group P212121
分子名称: DARPin 1238_G01
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FP9
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BU of 6fp9 by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_E11
分子名称: 1,2-ETHANEDIOL, DARPin 1238_E11, SULFATE ION
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FPB
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BU of 6fpb by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group I4
分子名称: CHLORIDE ION, DARPin 1238_G01
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.617 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FP8
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mTFP1/DARPin 1238_E11 complex in space group C2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DARPin1238_E11, ...
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.855 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
5YQ0
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BU of 5yq0 by Molmil
Crystal structure of secreted protein CofJ from ETEC.
分子名称: CALCIUM ION, CofJ
著者Oki, H, Kawahara, K, Maruno, T, Imai, T, Muroga, Y, Fukakusa, S, Iwashita, T, Kobayashi, Y, Matsuda, S, Kodama, T, Iida, T, Yoshida, T, Ohkubo, T, Nakamura, S.
登録日2017-11-04
公開日2018-06-27
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenicEscherichia colicolonization
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YPZ
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BU of 5ypz by Molmil
Crystal structure of minor pilin CofB from CFA/III complexed with N-terminal peptide fragment of CofJ
分子名称: CofB, CofJ
著者Oki, H, Kawahara, K, Maruno, T, Imai, T, Muroga, Y, Fukakusa, S, Iwashita, T, Kobayashi, Y, Matsuda, S, Kodama, T, Iida, T, Yoshida, T, Ohkubo, T, Nakamura, S.
登録日2017-11-04
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.521 Å)
主引用文献Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenicEscherichia colicolonization.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2C52
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BU of 2c52 by Molmil
Structural diversity in CBP p160 complexes
分子名称: CREB-BINDING PROTEIN, NUCLEAR RECEPTOR COACTIVATOR 1
著者Waters, L.C, Yue, B, Veverka, V, Renshaw, P.S, Bramham, J, Matsuda, S, Frenkiel, T, Kelly, G, Muskett, F.W, Carr, M.D, Heery, D.M.
登録日2005-10-25
公開日2006-03-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural diversity in p160/CREB-binding protein coactivator complexes.
J. Biol. Chem., 281, 2006
8SKQ
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BU of 8skq by Molmil
RNA oligonucleotide containing an alpha-(L)-threofuranosyl nucleic acid (TNA)
分子名称: TNA-containing RNA oligonucleotide
著者Harp, J.M, Egli, M.
登録日2023-04-20
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Shorter Is Better: The alpha-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
J.Am.Chem.Soc., 145, 2023
5VR4
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BU of 5vr4 by Molmil
RNA octamer containing 2'-F-4'-OMe U.
分子名称: COBALT TETRAAMMINE ION, RNA (5'-R(*CP*GP*AP*AP*(UMO)P*UP*CP*G)-3')
著者Harp, J.M, Egli, M.
登録日2017-05-10
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.
J. Am. Chem. Soc., 139, 2017
7XW8
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BU of 7xw8 by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
分子名称: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
著者Oki, H.
登録日2022-05-26
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022
7LO9
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BU of 7lo9 by Molmil
RNA dodecamer containing a GNA A residue
分子名称: Chains: A,B,C,D
著者Harp, J.M, Wawrzak, Z, Egli, M.
登録日2021-02-09
公開日2021-12-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs.
Nucleic Acids Res., 49, 2021
1WU3
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BU of 1wu3 by Molmil
Crystal structure of recombinant murine interferon beta
分子名称: Interferon beta
著者Senda, T, Saitoh, S, Mitsui, Y.
登録日2004-12-01
公開日2004-12-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Refined crystal structure of recombinant murine interferon-beta at 2.15 A resolution
J.Mol.Biol., 253, 1995
6VEM
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BU of 6vem by Molmil
Structure of RNA octamer
分子名称: COBALT HEXAMMINE(III), Modified Octamer RNA
著者Pallan, P.S, Egli, M.
登録日2020-01-02
公開日2020-11-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Synthesis, chirality-dependent conformational and biological properties of siRNAs containing 5'-(R)- and 5'-(S)-C-methyl-guanosine.
Nucleic Acids Res., 48, 2020
1HRF
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BU of 1hrf by Molmil
SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4
分子名称: HEREGULIN ALPHA
著者Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F.
登録日1994-07-21
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
EMBO J., 13, 1994
1HRE
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BU of 1hre by Molmil
SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4
分子名称: HEREGULIN ALPHA
著者Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F.
登録日1994-07-21
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
EMBO J., 13, 1994
5BV6
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BU of 5bv6 by Molmil
PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP
分子名称: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ...
著者Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W.
登録日2015-06-04
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J.Biol.Chem., 291, 2016
5C6C
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PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cAMP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CADMIUM ION, ...
著者Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W.
登録日2015-06-22
公開日2016-01-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J.Biol.Chem., 291, 2016

 

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