5VR4

RNA octamer containing 2'-F-4'-OMe U.

Summary for 5VR4

• Entry DOI: 10.2210/pdb5vr4/pdb
• Descriptor: RNA (5'-R(*CP*GP*AP*AP*(UMO)P*UP*CP*G)-3'), COBALT TETRAAMMINE ION (3 entities in total)
• Functional Keywords: rna
• Biological source: synthetic construct
• Total number of polymer chains: 4
• Total formula weight: 10361.37

Authors

Harp, J.M.,Egli, M. (deposition date: 2017-05-10, release date: 2017-10-04, Last modification date: 2023-10-04)

• Primary citation: Malek-Adamian, E.,Guenther, D.C.,Matsuda, S.,Martinez-Montero, S.,Zlatev, I.,Harp, J.,Burai Patrascu, M.,Foster, D.J.,Fakhoury, J.,Perkins, L.,Moitessier, N.,Manoharan, R.M.,Taneja, N.,Bisbe, A.,Charisse, K.,Maier, M.,Rajeev, K.G.,Egli, M.,Manoharan, M.,Damha, M.J.; 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.; J. Am. Chem. Soc., 139:14542-14555, 2017; PubMed: 28937776; DOI: 10.1021/jacs.7b07582

Experimental method

X-RAY DIFFRACTION (1.5 Å)