1B6C
 
 | | CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12 | | 分子名称: | FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I | | 著者 | Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J. | | 登録日 | 1999-01-13 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12.
Cell(Cambridge,Mass.), 96, 1999
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1OZJ
 | | Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution | | 分子名称: | SMAD 3, Smad binding element, ZINC ION | | 著者 | Chai, J, Wu, J.-W, Yan, N, Massague, J, Pavletich, N.P, Shi, Y. | | 登録日 | 2003-04-09 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding.
J.Biol.Chem., 278, 2003
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1YGS
 | | CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN | | 分子名称: | SMAD4 | | 著者 | Shi, Y, Hata, A, Lo, R.S, Massague, J, Pavletich, N.P. | | 登録日 | 1997-10-03 | | 公開日 | 1998-07-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A structural basis for mutational inactivation of the tumour suppressor Smad4.
Nature, 388, 1997
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1KHX
 | | Crystal structure of a phosphorylated Smad2 | | 分子名称: | Smad2 | | 著者 | Wu, J.-W, Hu, M, Chai, J, Seoane, J, Huse, M, Kyin, S, Muir, T.W, Fairman, R, Massague, J, Shi, Y. | | 登録日 | 2001-12-01 | | 公開日 | 2002-02-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.
Mol.Cell, 8, 2001
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1IAS
 | | CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | | 分子名称: | SULFATE ION, TGF-BETA RECEPTOR TYPE I | | 著者 | Huse, M, Muir, T.W, Chen, Y.-G, Kuriyan, J, Massague, J. | | 登録日 | 2001-03-23 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The TGF beta receptor activation process: an inhibitor- to substrate-binding switch.
Mol.Cell, 8, 2001
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2LAJ
 | | Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-16 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LTW
 | | YAP WW1 in complex with a Smad7 derived peptide | | 分子名称: | Smad7 derived peptide, Yorkie homolog | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | 登録日 | 2012-06-04 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LTY
 | | NEDD4L WW2 domain in complex with a Smad7 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | 登録日 | 2012-06-04 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LTX
 | | Smurf1 WW2 domain in complex with a Smad7 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | 登録日 | 2012-06-04 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LTZ
 | | Smurf2 WW3 domain in complex with a Smad7 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | 登録日 | 2012-06-04 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LAZ
 | | Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAW
 | | Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide | | 分子名称: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAX
 | | Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide. | | 分子名称: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LB0
 | | Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LTV
 | | YAP WW2 in complex with a Smad7 derived peptide | | 分子名称: | Smad7 derived peptide, Yorkie homolog | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | 登録日 | 2012-06-04 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LB3
 | | Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide | | 分子名称: | Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAY
 | | Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide | | 分子名称: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LB2
 | | Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3 | | 分子名称: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LB1
 | | Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide | | 分子名称: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | 登録日 | 2011-03-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2016-04-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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1MHD
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6H3R
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1FIN
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5ODG
 | | Crystal structure of Smad3-MH1 bound to the GGCT site. | | 分子名称: | CHLORIDE ION, DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 3, ... | | 著者 | Kaczmarska, Z, Marquez, J.A, Macias, M.J. | | 登録日 | 2017-07-05 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Nat Commun, 8, 2017
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5OD6
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1DEV
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