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1FYV
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR1
分子名称: TOLL-LIKE RECEPTOR 1
著者Xu, Y, Tao, X, Shen, B, Horng, T, Medzhitov, R, Manley, J.L, Tong, L.
登録日2000-10-03
公開日2000-11-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYX
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BU of 1fyx by Molmil
CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2
分子名称: TOLL-LIKE RECEPTOR 2
著者Xu, Y, Tao, X, Shen, B, Horng, T, Medzhitov, R, Manley, J.L, Tong, L.
登録日2000-10-03
公開日2000-11-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYW
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BU of 1fyw by Molmil
CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2
分子名称: TOLL-LIKE RECEPTOR 2
著者Xu, Y, Tao, X, Shen, B, Horng, T, Medzhitov, R, Manley, J.L, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2000-10-03
公開日2000-11-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
2OOE
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BU of 2ooe by Molmil
Crystal structure of HAT domain of murine CstF-77
分子名称: Cleavage stimulation factor 77 kDa subunit
著者Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L.
登録日2007-01-25
公開日2007-04-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
2OND
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BU of 2ond by Molmil
Crystal Structure of the HAT-C domain of murine CstF-77
分子名称: Cleavage stimulation factor 77 kDa subunit
著者Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L.
登録日2007-01-23
公開日2007-04-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
8EJM
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BU of 8ejm by Molmil
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DHX15, CHLORIDE ION, ...
著者Huang, J, Tong, L.
登録日2022-09-17
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
3FQI
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BU of 3fqi by Molmil
Crystal Structure of the Mouse Dom3Z
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Protein Dom3Z
著者Xiang, S, Tong, L.
登録日2009-01-07
公開日2009-02-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.013 Å)
主引用文献Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQG
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Crystal Structure of the S. pombe Rai1
分子名称: MAGNESIUM ION, Protein din1
著者Xiang, S, Tong, L.
登録日2009-01-07
公開日2009-02-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQJ
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Crystal Structure of the Mouse Dom3Z in Complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein Dom3Z
著者Xiang, S, Tong, L.
登録日2009-01-07
公開日2009-02-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQD
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Crystal Structure of the S. pombe Rat1-Rai1 Complex
分子名称: 5'-3' exoribonuclease 2, GLYCEROL, MAGNESIUM ION, ...
著者Xiang, S, Tong, L.
登録日2009-01-07
公開日2009-02-03
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
8GXL
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HUMAN SUGP1 433-577
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GXM
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HUMAN SUGP1 433-586
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
2I7T
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BU of 2i7t by Molmil
Structure of human CPSF-73
分子名称: Cleavage and polyadenylation specificity factor 73 kDa subunit, SULFATE ION, ZINC ION
著者Mandel, C.R, Zhang, H, Tong, L.
登録日2006-08-31
公開日2007-01-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
2I7V
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BU of 2i7v by Molmil
Structure of Human CPSF-73
分子名称: Cleavage and polyadenylation specificity factor 73 kDa subunit, SULFATE ION, ZINC ION
著者Mandel, C.R, Zhang, H, Tong, L.
登録日2006-08-31
公開日2007-01-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
2I7X
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BU of 2i7x by Molmil
Structure of Yeast CPSF-100 (Ydh1p)
分子名称: Protein CFT2
著者Mandel, C.R, Zhang, H, Gebauer, D, Tong, L.
登録日2006-08-31
公開日2007-01-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
3O2T
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BU of 3o2t by Molmil
Crystal structure of the N-terminal domain of human Symplekin
分子名称: 1,2-ETHANEDIOL, Symplekin
著者Tong, L, Xiang, K, Xiang, S.
登録日2010-07-22
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3O2Q
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BU of 3o2q by Molmil
Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex
分子名称: PHOSPHATE ION, RNA polymerase II CTD Serine-5 phosphopeptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
著者Tong, L, Xiang, K.
登録日2010-07-22
公開日2010-10-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3ODS
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BU of 3ods by Molmil
Crystal structure of the K185A mutant of the N-terminal domain of human Symplekin
分子名称: 1,2-ETHANEDIOL, Symplekin
著者Tong, L, Xiang, K.
登録日2010-08-11
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
4FC8
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Crystal structure of transcription regulator protein Rtr1 from Kluyveromyces lactis
分子名称: ZINC ION, transcription protein Rtr1
著者Xiang, K, Tong, L.
登録日2012-05-24
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity.
Nat Commun, 3, 2012
4H3H
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BU of 4h3h by Molmil
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7
分子名称: PHOSPHATE ION, Pol II CTD peptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
著者Xiang, K, Tong, L.
登録日2012-09-13
公開日2012-10-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
4H3K
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BU of 4h3k by Molmil
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
分子名称: Hexapeptide, PHOSPHATE ION, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
著者Xiang, K, Tong, L.
登録日2012-09-13
公開日2012-10-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
6BM0
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Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution
分子名称: Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
著者Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
登録日2017-11-12
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNH
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Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution
分子名称: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ...
著者Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
登録日2018-06-06
公開日2018-06-27
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLY
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Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution
分子名称: Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
著者Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
登録日2017-11-12
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3PQ1
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Crystal structure of human mitochondrial poly(A) polymerase (PAPD1)
分子名称: Poly(A) RNA polymerase
著者Bai, Y, Srivastava, S.K, Chang, J.H, Tong, L.
登録日2010-11-25
公開日2011-03-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase.
Mol.Cell, 41, 2011

 

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