1WYD
 
 | | Crystal Structure of Aspartyl-tRNA synthetase from Sulfolobus tokodaii | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, SULFATE ION, ... | | 著者 | Maeda, Y, Hossain, M.T, Ubukata, S, Suzuki, K, Sekiguchi, T, Takenaka, A. | | 登録日 | 2005-02-12 | | 公開日 | 2006-07-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the nondiscriminating aspartyl-tRNA synthetase from the crenarchaeon Sulfolobus tokodaii strain 7 reveals the recognition mechanism for two different tRNA anticodons
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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1A2X
 | | COMPLEX OF TROPONIN C WITH A 47 RESIDUE (1-47) FRAGMENT OF TROPONIN I | | 分子名称: | CALCIUM ION, TROPONIN C, TROPONIN I | | 著者 | Vassylyev, D.G, Takeda, S, Wakatsuki, S, Maeda, K, Maeda, Y. | | 登録日 | 1998-01-13 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
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3Q9T
 | | Crystal structure analysis of formate oxidase | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | 著者 | Doubayashi, D, Ootake, T, Maeda, Y, Oki, M, Tokunaga, Y, Sakurai, A, Nagaosa, Y, Mikami, B, Uchida, H. | | 登録日 | 2011-01-09 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Formate oxidase, an enzyme of the glucose-methanol-choline oxidoreductase family, has a His-Arg pair and 8-formyl-FAD at the catalytic site.
Biosci.Biotechnol.Biochem., 75, 2011
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1YWN
 | | Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine | | 分子名称: | N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA, Vascular endothelial growth factor receptor 2 | | 著者 | Miyazaki, Y, Matsunaga, S, Tang, J, Maeda, Y, Nakano, M, Philippe, R.J, Shibahara, M, Liu, W, Sato, H, Wang, L, Nolte, R.T. | | 登録日 | 2005-02-18 | | 公開日 | 2005-08-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
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1J1E
 | | Crystal structure of the 52kDa domain of human cardiac troponin in the Ca2+ saturated form | | 分子名称: | CALCIUM ION, Troponin C, Troponin I, ... | | 著者 | Takeda, S, Yamashita, A, Maeda, K, Maeda, Y. | | 登録日 | 2002-12-03 | | 公開日 | 2003-07-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
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1J1D
 | | Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form | | 分子名称: | CALCIUM ION, Troponin C, Troponin I, ... | | 著者 | Takeda, S, Yamashita, A, Maeda, K, Maeda, Y. | | 登録日 | 2002-12-03 | | 公開日 | 2003-07-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
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1V7N
 | | Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | | 分子名称: | Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin | | 著者 | Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R. | | 登録日 | 2003-12-18 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
Proc.Natl.Acad.Sci.USA, 101, 2004
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1V7M
 | | Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | | 分子名称: | Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin | | 著者 | Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R. | | 登録日 | 2003-12-18 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
Proc.Natl.Acad.Sci.USA, 101, 2004
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5H5G
 | | Staphylococcus aureus FtsZ-GDP in T and R states | | 分子名称: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Fujita, J, Harada, R, Maeda, Y, Saito, Y, Mizohata, E, Inoue, T, Shigeta, Y, Matsumura, H. | | 登録日 | 2016-11-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
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2ZGY
 | | PARM with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid segregation protein parM | | 著者 | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | | 登録日 | 2008-01-30 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability
Embo J., 27, 2008
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2ZGZ
 | | PARM with GMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plasmid segregation protein parM | | 著者 | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | | 登録日 | 2008-01-30 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability
Embo J., 27, 2008
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1IZN
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5H5H
 | | Staphylococcus aureus FtsZ-GDP R29A mutant in T state | | 分子名称: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Fujita, J, Harada, R, Maeda, Y, Saito, Y, Mizohata, E, Inoue, T, Shigeta, Y, Matsumura, H. | | 登録日 | 2016-11-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
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5H5I
 | | Staphylococcus aureus FtsZ-GDP R29A mutant in R state | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Fujita, J, Harada, R, Maeda, Y, Saito, Y, Mizohata, E, Inoue, T, Shigeta, Y, Matsumura, H. | | 登録日 | 2016-11-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
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2EFS
 | | Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution | | 分子名称: | General control protein GCN4 and Tropomyosin 1 alpha chain | | 著者 | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | | 登録日 | 2007-02-23 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
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2EFR
 | | Crystal structure of the c-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 1.8 angstroms resolution | | 分子名称: | General control protein GCN4 and Tropomyosin 1 alpha chain | | 著者 | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | | 登録日 | 2007-02-23 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
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2D3E
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5TNO
 | | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, SODIUM ION, ... | | 著者 | Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, H, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S. | | 登録日 | 2016-10-14 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
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5TNT
 | | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, N-[(1S,4S,7R)-2-(3-amino-4-chloro[1,2]oxazolo[5,4-c]pyridin-7-yl)-2-azabicyclo[2.2.1]heptan-7-yl]-2-chloro-4-(3-methyl-1H-1,2,4-triazol-1-yl)benzamide, ... | | 著者 | Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, A, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S. | | 登録日 | 2016-10-14 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
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3WQT
 | | Staphylococcus aureus FtsA complexed with AMPPNP | | 分子名称: | CHLORIDE ION, Cell division protein FtsA, MAGNESIUM ION, ... | | 著者 | Fujita, J, Maeda, Y, Miyazaki, Y, Inoue, T, Matsumura, H. | | 登録日 | 2014-02-01 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of FtsA from Staphylococcus aureus
FEBS Lett., 588, 2014
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3WQU
 | | Staphylococcus aureus FtsA complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION | | 著者 | Fujita, J, Maeda, Y, Miyazaki, Y, Inoue, T, Matsumura, H. | | 登録日 | 2014-02-01 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of FtsA from Staphylococcus aureus
FEBS Lett., 588, 2014
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1IO0
 | | CRYSTAL STRUCTURE OF TROPOMODULIN C-TERMINAL HALF | | 分子名称: | TROPOMODULIN, ZINC ION | | 著者 | Krieger, I, Kostyukova, A, Yamashita, A, Maeda, Y. | | 登録日 | 2000-12-14 | | 公開日 | 2002-11-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of the C-terminal half of tropomodulin and structural basis of actin filament pointed-end capping.
Biophys.J., 83, 2002
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3AAA
 | | Crystal Structure of Actin capping protein in complex with V-1 | | 分子名称: | F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, ISOPROPYL ALCOHOL, ... | | 著者 | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | | 登録日 | 2009-11-12 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
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2Y83
 | | Actin filament pointed end | | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Narita, A, Oda, T, Maeda, Y. | | 登録日 | 2011-02-02 | | 公開日 | 2011-03-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (22.9 Å) | | 主引用文献 | Structural Basis for the Slow Dynamics of the Actin Filament Pointed End.
Embo J., 30, 2011
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2ZWH
 | | Model for the F-actin structure | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Oda, T, Iwasa, M, Aihara, T, Maeda, Y, Narita, A. | | 登録日 | 2008-12-05 | | 公開日 | 2009-01-20 | | 最終更新日 | 2017-10-11 | | 実験手法 | FIBER DIFFRACTION (3.3 Å) | | 主引用文献 | The nature of the globular- to fibrous-actin transition.
Nature, 457, 2009
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