5NPY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5npy by Molmil](/molmil-images/mine/5npy) | Crystal structure of Helicobacter pylori flagellar hook protein FlgE2 | 分子名称: | Flagellar basal body protein, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | 著者 | Loconte, V, Zanotti, G, Kekez, I, Matkovic-Calogovic, D. | 登録日 | 2017-04-19 | 公開日 | 2017-11-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural characterization of FlgE2 protein from Helicobacter pylori hook. FEBS J., 284, 2017
|
|
6SUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sug by Molmil](/molmil-images/mine/6sug) | Crystal structure of transthyretin in complex with 3-deoxytolcapone, a tolcapone analogue | 分子名称: | 3-deoxytolcapone, Transthyretin | 著者 | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | 登録日 | 2019-09-14 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin. Bioorg.Chem., 103, 2020
|
|
6R66
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r66 by Molmil](/molmil-images/mine/6r66) | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | 分子名称: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | 登録日 | 2019-03-26 | 公開日 | 2019-09-11 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
|
|
6R67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r67 by Molmil](/molmil-images/mine/6r67) | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | 分子名称: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | 登録日 | 2019-03-26 | 公開日 | 2019-09-11 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
|
|
6R68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r68 by Molmil](/molmil-images/mine/6r68) | Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | 分子名称: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | 登録日 | 2019-03-26 | 公開日 | 2019-09-11 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
|
|
6R6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r6i by Molmil](/molmil-images/mine/6r6i) | Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin | 著者 | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | 登録日 | 2019-03-27 | 公開日 | 2019-09-11 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.467 Å) | 主引用文献 | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
|
|
6SUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6suh by Molmil](/molmil-images/mine/6suh) | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone, a tolcapone analogue | 分子名称: | 3-O-methyltolcapone, Transthyretin | 著者 | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | 登録日 | 2019-09-14 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin. Bioorg.Chem., 103, 2020
|
|
8C86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c86 by Molmil](/molmil-images/mine/8c86) | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 2 | 分子名称: | (2,4-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | 登録日 | 2023-01-18 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
|
|
8C85
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c85 by Molmil](/molmil-images/mine/8c85) | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 | 分子名称: | (3,5-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | 登録日 | 2023-01-18 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
|
|
4INN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4inn by Molmil](/molmil-images/mine/4inn) | Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, HP1028 | 著者 | Barison, N, Cendron, L, Loconte, V, Zanotti, G. | 登録日 | 2013-01-05 | 公開日 | 2013-07-31 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family. Acta Crystallogr.,Sect.D, 69, 2013
|
|