1FNF
 
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1TEN
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1CD8
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1BAF
 | | 2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN | | 分子名称: | IGG1-KAPPA AN02 FAB (HEAVY CHAIN), IGG1-KAPPA AN02 FAB (LIGHT CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE | | 著者 | Leahy, D.J, Brunger, A.T, Fox, R.O, Hynes, T.R. | | 登録日 | 1992-01-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | 2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
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1ZOP
 | | CD11A I-DOMAIN WITH BOUND MAGNESIUM ION | | 分子名称: | CHLORIDE ION, I-DOMAIN FRAGMENT OF LFA-1, MANGANESE (II) ION | | 著者 | Leahy, D.J, Qu, A. | | 登録日 | 1996-06-21 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
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1ZOO
 | | CD11A I-DOMAIN WITH BOUND MAGNESIUM ION | | 分子名称: | CHLORIDE ION, LEUKOCYTE ADHESION GLYCOPROTEIN, MAGNESIUM ION | | 著者 | Leahy, D.J, Qu, A. | | 登録日 | 1996-06-21 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
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1ZON
 | | CD11A I-DOMAIN WITHOUT BOUND CATION | | 分子名称: | LEUKOCYTE ADHESION GLYCOPROTEIN | | 著者 | Leahy, D.J, Qu, A. | | 登録日 | 1996-06-20 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
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1LFA
 | | CD11A I-DOMAIN WITH BOUND MN++ | | 分子名称: | CD11A, CHLORIDE ION, MANGANESE (II) ION | | 著者 | Leahy, D.J, Qu, A. | | 登録日 | 1995-09-08 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.
Proc.Natl.Acad.Sci.USA, 92, 1995
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1M6B
 | | Structure of the HER3 (ERBB3) Extracellular Domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor protein-tyrosine kinase erbB-3, ... | | 著者 | Leahy, D.J, Cho, H.-S. | | 登録日 | 2002-07-15 | | 公開日 | 2002-08-02 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the extracellular region of HER3 reveals an interdomain tether.
Science, 297, 2002
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6JFV
 | | The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14) | | 分子名称: | Keratin, type I cytoskeletal 14, type II cytoskeletal 5 | | 著者 | Kim, M.S, Lee, C.H, Coulombe, P.A, Leahy, D.J. | | 登録日 | 2019-02-12 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly.
Structure, 28, 2020
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2IC2
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1SZH
 | | Crystal Structure of C. elegans HER-1 | | 分子名称: | ACETATE ION, Her-1 protein | | 著者 | Hamaoka, B.Y, Dann III, C.E, Geisbrecht, B.V, Leahy, D.J. | | 登録日 | 2004-04-05 | | 公開日 | 2004-08-10 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A.
Proc.Natl.Acad.Sci.USA, 101, 2004
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3ODN
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2ORX
 | | Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin | | 分子名称: | Neuropilin-1 | | 著者 | Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. | | 登録日 | 2007-02-05 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for ligand and heparin binding to neuropilin B domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ORZ
 | | Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin | | 分子名称: | Neuropilin-1, Tuftsin | | 著者 | Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. | | 登録日 | 2007-02-05 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for ligand and heparin binding to neuropilin B domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2IBB
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2IBG
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3TNU
 | | Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14) | | 分子名称: | Keratin, type I cytoskeletal 14, type II cytoskeletal 5 | | 著者 | Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A. | | 登録日 | 2011-09-02 | | 公開日 | 2012-06-20 | | 最終更新日 | 2012-08-01 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
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3U9U
 | | Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479 | | 分子名称: | Fab Heavy Chain, Fab Light Chain, Receptor tyrosine-protein kinase erbB-4 | | 著者 | Hollmen, M, Liu, P, Wildiers, H, Reinvall, I, Vandorpe, T, Smeets, A, Deraedt, K, Vahlberg, T, Joensuu, H, Leahy, D.J, Schoffski, P, Elenius, K. | | 登録日 | 2011-10-19 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Proteolytic processing of ErbB4 in breast cancer.
Plos One, 7, 2012
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3U7U
 | | Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4 | | 著者 | Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J. | | 登録日 | 2011-10-14 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | A single ligand is sufficient to activate EGFR dimers.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3U2P
 | | Crystal structure of N-terminal three extracellular domains of ErbB4/Her4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4 | | 著者 | Liu, P, Bouyain, S, Elgenbrot, C, Leahy, D.J. | | 登録日 | 2011-10-04 | | 公開日 | 2011-11-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether.
Protein Sci., 21, 2012
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1S78
 | | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ... | | 著者 | Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X. | | 登録日 | 2004-01-29 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
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2OGB
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1VHH
 | | A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG | | 分子名称: | SONIC HEDGEHOG, SULFATE ION, ZINC ION | | 著者 | Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J. | | 登録日 | 1995-10-03 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
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1OT8
 | | Structure of the Ankyrin Domain of the Drosophila Notch Receptor | | 分子名称: | MAGNESIUM ION, Neurogenic locus Notch protein | | 著者 | Zweifel, M.E, Leahy, D.J, Hughson, F.M, Barrick, D. | | 登録日 | 2003-03-21 | | 公開日 | 2003-10-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., 12, 2003
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