7TW7
 
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7TW9
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7TW8
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8U7B
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8FRK
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8FRJ
 | | Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946 | | 分子名称: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION | | 著者 | Kottur, J, Aggarwal, A.K. | | 登録日 | 2023-01-07 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
Plos Pathog., 19, 2023
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4Q43
 | | Polymerase-damaged DNA complex | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*T*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*(RDG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | | 著者 | Kottur, J, Sharma, A, Nair, D.T. | | 登録日 | 2014-04-13 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic
Structure, 23, 2015
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4Q45
 | | DNA Polymerase- damaged DNA complex | | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*TP*CP*TP*A*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*AP*GP*GP*(RDG)P*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | | 著者 | Kottur, J, Sharma, A, Nair, D.T. | | 登録日 | 2014-04-13 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.176 Å) | | 主引用文献 | Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic
Structure, 23, 2015
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6IG1
 | | DNA polymerase IV - DNA ternary complex 10 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN3, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2018-09-21 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res., 46, 2018
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5YUY
 | | DNA polymerase IV - DNA ternary complex 9 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YUR
 | | DNA polymerase IV - DNA ternary complex 1 | | 分子名称: | DNA polymerase IV, DTN, SODIUM ION, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.035 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YUT
 | | DNA polymerase IV - DNA ternary complex 3 | | 分子名称: | DNA polymerase IV, DTN, MAGNESIUM ION, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YUZ
 | | DNA polymerase IV - DNA ternary complex 11 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res., 46, 2018
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5YUU
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5YUS
 | | DNA polymerase IV - DNA ternary complex 2 | | 分子名称: | DNA polymerase IV, DTN, MAGNESIUM ION, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YUV
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5YUX
 | | DNA polymerase IV - DNA ternary complex 8 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YUW
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5YYE
 | | DNA polymerase IV - ternary complex 16 | | 分子名称: | 5'-O-[hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]thymidine, DNA polymerase IV, DTN2, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-12-08 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.325 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YV1
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5YV0
 | | DNA polymerase IV - DNA ternary complex 12 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res., 46, 2018
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5YV3
 | | DNA polymerase IV - DNA ternary complex 7 | | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-11-23 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5YV2
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5YYD
 | | DNA polymerase IV - ternary complex 15 | | 分子名称: | 5'-O-[hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]thymidine, DNA polymerase IV, DTN2, ... | | 著者 | Kottur, J, Nair, D.T. | | 登録日 | 2017-12-08 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res., 46, 2018
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5ZLV
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