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2MHQ
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BU of 2mhq by Molmil
Solution structure of the major factor VIII binding region on von Willebrand factor
分子名称: von Willebrand factor
著者Shiltagh, N, Kirkpatrick, J, Cabrita, L.D, McKinnon, T.A.J, Thalassinos, K, Tuddenham, E.G.D, Hansen, D.F.
登録日2013-12-02
公開日2014-05-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of the major factor VIII binding region on von Willebrand factor.
Blood, 123, 2014
2MHP
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BU of 2mhp by Molmil
Solution structure of the major factor VIII binding region on von Willebrand factor
分子名称: von Willebrand factor
著者Shiltagh, N, Kirkpatrick, J, Cabrita, L.D, McKinnon, T.A.J, Thalassinos, K, Tuddenham, E.G.D, Hansen, D.F.
登録日2013-12-02
公開日2014-05-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of the major factor VIII binding region on von Willebrand factor.
Blood, 123, 2014
8RZ6
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BU of 8rz6 by Molmil
SeMet derivative structure of the condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase
分子名称: FORMIC ACID, GLYCEROL, POTASSIUM ION, ...
著者Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T.
登録日2024-02-12
公開日2024-06-26
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8AOU
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BU of 8aou by Molmil
Solution NMR structure of full-length Nsp1 from SARS-CoV-2.
分子名称: Host translation inhibitor nsp1
著者Wang, Y, Kirkpatrick, J.P, Carlomagno, T.
登録日2022-08-08
公開日2022-12-28
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2.
Structure, 31, 2023
8QNF
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BU of 8qnf by Molmil
Crystal structure of the Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase
分子名称: Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase, FORMIC ACID, GLYCEROL, ...
著者Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
6O22
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BU of 6o22 by Molmil
Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.
分子名称: Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ...
著者Danilenko, N, Carlomagno, T, Kirkpatrick, J.P.
登録日2019-02-22
公開日2019-07-31
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Histone chaperone exploits intrinsic disorder to switch acetylation specificity.
Nat Commun, 10, 2019
6F0Y
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BU of 6f0y by Molmil
Rtt109 peptide bound to Asf1
分子名称: Histone chaperone ASF1, histone acetyltransferase Rtt109 C-terminus
著者Lercher, L, Kirkpatrick, J.P, Carlomagno, T.
登録日2017-11-21
公開日2017-12-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.
Nucleic Acids Res., 46, 2018
5I3D
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BU of 5i3d by Molmil
Sulfolobus solfataricus beta-glycosidase - E387Y mutant
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-galactosidase
著者Iglesias-Fernandez, J, Hancock, S.M, Lee, S.S, McAuley, K.E, Fordham-Skelton, A, Rovira, C, Davis, B.D.
登録日2016-02-10
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase.
Nat. Chem. Biol., 13, 2017
6ROY
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BU of 6roy by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM)
著者Krausze, J, Sikorska, J, Carlomagno, T.
登録日2019-05-13
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6ROZ
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BU of 6roz by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM)
著者Krausze, J, Sikorska, J, Carlomagno, T.
登録日2019-05-13
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
4TN3
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BU of 4tn3 by Molmil
Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha
分子名称: TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION
著者Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C.
登録日2014-06-03
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1989 Å)
主引用文献Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Proc.Natl.Acad.Sci.USA, 111, 2014
6R5G
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BU of 6r5g by Molmil
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
分子名称: ITSM, Tyrosine-protein phosphatase non-receptor type 11
著者Marasco, M.
登録日2019-03-25
公開日2020-02-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
4PYW
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BU of 4pyw by Molmil
1.92 angstrom crystal structure of A1AT:TTAI ternary complex
分子名称: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
著者Nyon, M.P, Day, J, Gooptu, B.
登録日2014-03-28
公開日2015-06-10
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015

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件を2024-07-10に公開中

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