2MHQ

Solution structure of the major factor VIII binding region on von Willebrand factor

Summary for 2MHQ

• Entry DOI: 10.2210/pdb2mhq/pdb
• Related: 2MHP
• Descriptor: von Willebrand factor (1 entity in total)
• Functional Keywords: von willebrand factor, factor viii, ensemble refinement, blood clotting
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P04275
• Total number of polymer chains: 1
• Total formula weight: 11351.28

Authors

Shiltagh, N.,Kirkpatrick, J.,Cabrita, L.D.,McKinnon, T.A.J.,Thalassinos, K.,Tuddenham, E.G.D.,Hansen, D.F. (deposition date: 2013-12-02, release date: 2014-05-14, Last modification date: 2023-06-14)

• Primary citation: Shiltagh, N.,Kirkpatrick, J.,Cabrita, L.D.,McKinnon, T.A.,Thalassinos, K.,Tuddenham, E.G.,Hansen, D.F.; Solution structure of the major factor VIII binding region on von Willebrand factor.; Blood, 123:4143-4151, 2014; PubMed: 24700780; DOI: 10.1182/blood-2013-07-517086

Experimental method

SOLUTION NMR