5TSG
 
 | | PilB from Geobacter metallireducens bound to ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | McCallum, M, Tammam, S, Khan, A, Burrows, L, Howell, P.L. | | 登録日 | 2016-10-28 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.4011 Å) | | 主引用文献 | The molecular mechanism of the type IVa pilus motors.
Nat Commun, 8, 2017
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5TSH
 | | PilB from Geobacter metallireducens bound to AMP-PNP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | McCallum, M, Tammam, S, Khan, A, Burrows, L, Howell, P.L. | | 登録日 | 2016-10-28 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The molecular mechanism of the type IVa pilus motors.
Nat Commun, 8, 2017
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7N99
 | | SDE2 SAP domain apo structure | | 分子名称: | Isoform 2 of Replication stress response regulator SDE2 | | 著者 | Paung, Y, Weinheimer, A.S, Rageul, J, Khan, A, Ho, B, Tong, M, Alphonse, S, Seeliger, M.A, Kim, H. | | 登録日 | 2021-06-17 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks.
J.Biol.Chem., 298, 2022
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4XRT
 | | Crystal structure of the di-domain ARO/CYC StfQ from the steffimycin biosynthetic pathway | | 分子名称: | FORMIC ACID, StfQ Aromatase/Cyclase | | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | | 登録日 | 2015-01-21 | | 公開日 | 2015-12-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XRW
 | | Crystal structure of the di-domain ARO/CYC BexL from the BE-7585A biosynthetic pathway | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BexL | | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | | 登録日 | 2015-01-21 | | 公開日 | 2015-12-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5UCI
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | (2,4-Dihydroxy-3-(hydroxymethyl)-5-isopropylphenyl)(isoindolin-2-yl)methanone, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Peng, S, Balch, M, Matts, R, Deng, J. | | 登録日 | 2016-12-22 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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5UCJ
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | (5-fluoroisoindolin-2-yl)(4-hydroxy-5-isopropylbenzo[d]isoxazol-7-yl)methanone, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-beta | | 著者 | Peng, S, Balch, M, Matts, R, Deng, J. | | 登録日 | 2016-12-22 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.693 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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5UCH
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | 2-(5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylphenyl)acetonitrile, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Peng, S, Balch, M, Matts, R, Deng, J. | | 登録日 | 2016-12-22 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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5UC4
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Deng, J, Peng, S, Balch, M, Matts, R. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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8GIJ
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7W5U
 | | Acetyl-CoA Carboxylase-AccB | | 分子名称: | Acetyl-CoA carboxylase complex, beta-chain, GLYCEROL, ... | | 著者 | Ali, I, Zheng, J. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations.
Comput Biol Med, 145, 2022
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7QUR
 | | SARS-CoV-2 Spike with ethylbenzamide-tri-iodo Siallyllactose, C3 symmetry | | 分子名称: | 2,3,5-tris(iodanyl)benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-01 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
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7QUS
 | | SARS-CoV-2 Spike, C3 symmetry | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-08 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
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5NC8
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5WLE
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5WLF
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5UDE
 | | Crystal Structure of RSV F B9320 DS-Cav1 | | 分子名称: | Fusion glycoprotein F0, SULFATE ION | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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5UDC
 | | Crystal Structure of RSV F A2 Bound to MEDI8897 | | 分子名称: | CHLORIDE ION, Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, ... | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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5UDD
 | | Crystal Structure of RSV F B9320 Bound to MEDI8897 | | 分子名称: | Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ... | | 著者 | McLellan, J.S. | | 登録日 | 2016-12-26 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
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4BHT
 | | Structural Determinants of Cofactor Specificity and Domain Flexibility in Bacterial Glutamate Dehydrogenases | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, NADP-SPECIFIC GLUTAMATE DEHYDROGENASE, ... | | 著者 | Oliveira, T, Sharkey, M, Engel, P, Khan, A. | | 登録日 | 2013-04-06 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Nadp(+) -Dependent Glutamate Dehydrogenase from Escherichia Coli: Reflections on the Basis of Coenzyme Specificity in the Family of Glutamate Dehydrogenases.
FEBS J., 280, 2013
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6GDY
 | | Crystal structure of 2OG oxygenase JMJD6 (aa 1-343) in complex with Fe(II) and 2OG | | 分子名称: | 2-OXOGLUTARIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... | | 著者 | Islam, M.S, Schofield, C.J, McDonough, M.A. | | 登録日 | 2018-04-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.
J.Biol.Chem., 294, 2019
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8UBZ
 | | Choline-bound FLVCR1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | | 著者 | Hite, R.K, Son, Y. | | 登録日 | 2023-09-25 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
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8UBX
 | | Ethanolamine-bound FLVCR1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, ETHANOLAMINE, Heme transporter FLVCR1 | | 著者 | Hite, R.K, Son, Y. | | 登録日 | 2023-09-25 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
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8UBY
 | | Choline-bound FLVCR1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | | 著者 | Hite, R.K, Son, Y. | | 登録日 | 2023-09-25 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
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8UC0
 | | Endogenous ligand bound FLVCR1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Heme transporter FLVCR1 | | 著者 | Hite, R.K, Son, Y. | | 登録日 | 2023-09-25 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
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