3NRX
 
 | | Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein | | 分子名称: | Protein regulator of cytokinesis 1 | | 著者 | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | | 登録日 | 2010-06-30 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
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3NRY
 | | Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein | | 分子名称: | Protein regulator of cytokinesis 1 | | 著者 | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | | 登録日 | 2010-07-01 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
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8VT7
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8VRD
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8VRJ
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8VRK
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8VA2
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5KMG
 | | Near-atomic cryo-EM structure of PRC1 bound to the microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. | | 登録日 | 2016-06-27 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Near-atomic cryo-EM structure of PRC1 bound to the microtubule.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6E7C
 | | 14-pf 3-start GMPCPP-human alpha1B/beta2B microtubules | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Ti, S.C, Alushin, G.M, Kapoor, T.M. | | 登録日 | 2018-07-25 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability.
Dev. Cell, 47, 2018
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6E7B
 | | 13-pf 3-start GMPCPP-human alpha1B/beta3 microtubules | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Ti, S.C, Alushin, G.M, Kapoor, T.M. | | 登録日 | 2018-07-25 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability.
Dev. Cell, 47, 2018
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1NLP
 | | STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | C-SRC, NL2 (MN8-MN1-PLPPLP) | | 著者 | Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. | | 登録日 | 1996-08-04 | | 公開日 | 1997-01-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis.
Chem.Biol., 3, 1996
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1NLO
 | | STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | C-SRC, NL1 (MN7-MN2-MN1-PLPPLP) | | 著者 | Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. | | 登録日 | 1996-08-04 | | 公開日 | 1997-01-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis.
Chem.Biol., 3, 1996
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5IJ9
 | | Cryo EM density of microtubule assembled from human TUBB3-D417H mutant | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ti, S.C, Pamula, M.C, Howes, S.C, Duellberg, C, Cade, N.I, Kleiner, R.E, Forth, S, Surrey, T, Nogales, E, Kapoor, T.M. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.
Dev.Cell, 37, 2016
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5IJ0
 | | Cryo EM density of microtubule assembled from human TUBB3 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ti, S.-C, Pamula, M.C, Howes, S.C, Duellberg, C, Nicholas, C.I, Kleiner, R.E, Forth, S, Surrey, T, Nogales, E, Kapoor, T.M. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.
Dev.Cell, 37, 2016
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4L3I
 | | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | | 分子名称: | Protein regulator of cytokinesis 1 | | 著者 | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | | 登録日 | 2013-06-06 | | 公開日 | 2013-07-17 | | 最終更新日 | 2013-08-07 | | 実験手法 | X-RAY DIFFRACTION (3.6005 Å) | | 主引用文献 | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
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4L6Y
 | | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | | 分子名称: | Protein regulator of cytokinesis 1 | | 著者 | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | | 登録日 | 2013-06-13 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3015 Å) | | 主引用文献 | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
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6NYV
 | | Structure of spastin AAA domain in complex with a quinazoline-based inhibitor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, N-(3-tert-butyl-1H-pyrazol-5-yl)-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, SULFATE ION, ... | | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | | 登録日 | 2019-02-12 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.425 Å) | | 主引用文献 | Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.
J. Am. Chem. Soc., 141, 2019
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6NYW
 | | Structure of spastin AAA domain N527C mutant in complex with 8-fluoroquinazoline-based inhibitor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, N-(5-tert-butyl-1H-pyrazol-3-yl)-8-fluoro-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, ... | | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | | 登録日 | 2019-02-12 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.
J. Am. Chem. Soc., 141, 2019
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6OR6
 | | Full-length S. pombe Mdn1 in the presence of AMPPNP (tail region) | | 分子名称: | Midasin | | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | | 登録日 | 2019-04-29 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.
Cell, 175, 2018
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6V69
 | | Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | | 分子名称: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex.
Cell, 180, 2020
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6V6C
 | | Structure of GCP6 in the native human gamma-tubulin ring complex | | 分子名称: | Gamma-tubulin complex component 6 | | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex.
Cell, 180, 2020
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6V6S
 | | Structure of the native human gamma-tubulin ring complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Gamma-tubulin complex component 2, ... | | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | | 登録日 | 2019-12-05 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex.
Cell, 180, 2020
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6V5V
 | | Structure of gamma-tubulin in the native human gamma-tubulin ring complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Tubulin gamma-1 chain | | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex.
Cell, 180, 2020
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6V6B
 | | Structures of GCP2 and GCP3 in the native human gamma-tubulin ring complex | | 分子名称: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3 | | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex.
Cell, 180, 2020
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6X0U
 | | Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge | | 分子名称: | Gamma-tubulin complex component 3, Gamma-tubulin complex component 6, Mitotic-spindle organizing protein 1 | | 著者 | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | | 登録日 | 2020-05-17 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex.
Cell Rep, 31, 2020
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