1KHO
 
 | | Crystal Structure Analysis of Clostridium perfringens alpha-Toxin Isolated from Avian Strain SWCP | | 分子名称: | ZINC ION, alpha-toxin | | 著者 | Justin, N, Moss, D.S, Titball, R.W, Basak, A.K. | | 登録日 | 2001-11-30 | | 公開日 | 2002-06-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
Biochemistry, 41, 2002
|
|
4X3E
 | |
5HYN
 | | Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide | | 分子名称: | H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ... | | 著者 | Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J. | | 登録日 | 2016-02-01 | | 公開日 | 2016-05-11 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
|
|
2WXT
 | | Clostridium perfringens alpha-toxin strain NCTC8237 | | 分子名称: | CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE C, ... | | 著者 | Justin, N, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-10 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2010
|
|
3IIY
 | | Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide | | 分子名称: | Histone H1K26 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
|
|
3IIW
 | | Crystal structure of Eed in complex with a trimethylated histone H3K27 peptide | | 分子名称: | Histone H3 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
|
|
3IJ0
 | | Crystal structure of Eed in complex with a trimethylated histone H3K9 peptide | | 分子名称: | Histone H3K9 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
|
|
3IJC
 | | Crystal structure of Eed in complex with NDSB-195 | | 分子名称: | ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-04 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
|
|
3IJ1
 | | Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide | | 分子名称: | Histone H4K20 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
|
|
5LS6
 | | Structure of Human Polycomb Repressive Complex 2 (PRC2) with inhibitor | | 分子名称: | 1-[(1~{R})-1-[1-[2,2-bis(fluoranyl)propyl]piperidin-4-yl]ethyl]-~{N}-[(4-methoxy-6-methyl-2-oxidanylidene-3~{H}-pyridin-3-yl)methyl]-2-methyl-indole-3-carboxamide, Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2, Jarid2 K116me3, ... | | 著者 | Zhang, Y, Justin, N, Chen, S, Wilson, J, Gamblin, S. | | 登録日 | 2016-08-22 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | | 主引用文献 | Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas.
J. Med. Chem., 59, 2016
|
|
1XQH
 | | Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH | | 分子名称: | 9-mer peptide from tumor protein p53, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | | 著者 | Chuikov, S, Kurash, J.K, Wilson, J.R, Xiao, B, Justin, N, Ivanov, G.S, McKinney, K, Tempst, P, Prives, C, Gamblin, S.J, Barlev, N.A, Reinberg, D. | | 登録日 | 2004-10-12 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Regulation of p53 activity through lysine methylation
Nature, 432, 2004
|
|
5M5G
 | | Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2) | | 分子名称: | Fragment from molecular 2 (region containing putative polycomb protein Suz12), HISTONE H3 11-Mer peptide, Putative uncharacterized protein, ... | | 著者 | Zhang, Y, Justin, N, Wilson, J, Gamblin, S. | | 登録日 | 2016-10-21 | | 公開日 | 2017-01-11 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Science, 354, 2016
|
|
1I4T
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN | | 分子名称: | ARFAPTIN 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-23 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
|
|
1I4L
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41) | | 分子名称: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-22 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
|
|
1I4D
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21) | | 分子名称: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-20 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
|
|
1I49
 | | CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN | | 分子名称: | ARFAPTIN 2 | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-20 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
|
|
2WXU
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | 分子名称: | CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE C, ... | | 著者 | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-10 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2010
|
|
2WY6
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | 分子名称: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-12 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2011
|
|
4AGH
 | | Structural features of ssDNA binding protein MoSub1 from Magnaporthe oryzae | | 分子名称: | MOSUB1, TRANSCRIPTION COFACTOR | | 著者 | Huang, J, Zhao, Y, Huang, D, liu, J, Peng, Y. | | 登録日 | 2012-01-27 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | | 主引用文献 | Structural Features of the Single-Stranded DNA-Binding Protein Mosub1 from Magnaporthe Oryzae.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
1CA1
 | |
1QMD
 | | calcium bound closed form alpha-toxin from Clostridium perfringens | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE C, ZINC ION | | 著者 | Naylor, C.E, Miller, J, Titball, R.W, Basak, A.K. | | 登録日 | 1999-09-27 | | 公開日 | 2000-02-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin
J.Mol.Biol., 294, 1999
|
|
1QM6
 | | Closed form of Clostridium perfringens alpha-toxin strain NCTC8237 | | 分子名称: | PHOSPHOLIPASE C, ZINC ION | | 著者 | Naylor, C.E, Miller, J, Titball, R.W, Basak, A.K. | | 登録日 | 1999-09-21 | | 公開日 | 1999-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin
J.Mol.Biol., 294, 1999
|
|
1OLP
 | | Alpha Toxin from Clostridium Absonum | | 分子名称: | ALPHA-TOXIN, CALCIUM ION, ZINC ION | | 著者 | Briggs, D.C, Basak, A.K. | | 登録日 | 2003-08-11 | | 公開日 | 2003-10-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Clostridium Absonum Alpha-Toxin: New Insights Into Clostridial Phospholipase C Substrate Binding and Specificity
J.Mol.Biol., 333, 2003
|
|
