4S1Z
 
 | | Crystal structure of TRABID NZF1 in complex with K29 linked di-Ubiquitin | | 分子名称: | Ubiquitin, Ubiquitin thioesterase ZRANB1, ZINC ION | | 著者 | Kristariyanto, Y.A, Abdul Rehman, S.A, Campbell, D.G, Morrice, N.A, Johnson, C, Toth, R, Kulathu, Y. | | 登録日 | 2015-01-16 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.
Mol.Cell, 58, 2015
|
|
4S22
 | | Crystal structure of K29 linked di-Ubiquitin | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ... | | 著者 | Kristariyanto, Y.A, Abdul Rehman, S.A, Campbell, D.G, Morrice, N.A, Johnson, C, Toth, R, Kulathu, Y. | | 登録日 | 2015-01-17 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.
Mol.Cell, 58, 2015
|
|
5N38
 | | S65DParkin and pUB complex | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ... | | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | | 登録日 | 2017-02-08 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5N2W
 | | WT-Parkin and pUB complex | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ... | | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | | 登録日 | 2017-02-08 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
|
|
1XGK
 | | CRYSTAL STRUCTURE OF N12G AND A18G MUTANT NMRA | | 分子名称: | CHLORIDE ION, GLYCEROL, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, ... | | 著者 | Lamb, H.K, Ren, J, Park, A, Johnson, C, Leslie, K, Cocklin, S, Thompson, P, Mee, C, Cooper, A, Stammers, D.K, Hawkins, A.R. | | 登録日 | 2004-09-17 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis
Protein Sci., 13, 2004
|
|
2VUS
 | | Crystal structure of unliganded NmrA-AreA zinc finger complex | | 分子名称: | CHLORIDE ION, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... | | 著者 | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | | 登録日 | 2008-05-30 | | 公開日 | 2008-07-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
|
|
2VUT
 | | Crystal structure of NAD-bound NmrA-AreA zinc finger complex | | 分子名称: | CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | | 登録日 | 2008-05-30 | | 公開日 | 2008-07-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
|
|
2VUU
 | | Crystal structure of NADP-bound NmrA-AreA zinc finger complex | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... | | 著者 | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | | 登録日 | 2008-05-30 | | 公開日 | 2008-07-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
J.Mol.Biol., 381, 2008
|
|
1TI7
 | | CRYSTAL STRUCTURE OF NMRA, A NEGATIVE TRANSCRIPTIONAL REGULATOR, IN COMPLEX WITH NADP AT 1.7A RESOLUTION | | 分子名称: | CHLORIDE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Lamb, H.K, Leslie, K, Dodds, A.L, Nutley, M, Cooper, A, Johnson, C, Thompson, P, Stammers, D.K, Hawkins, A.R. | | 登録日 | 2004-06-02 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides.
J.Biol.Chem., 278, 2003
|
|
5UHV
 | | wild-type NRas bound to GppNHp | | 分子名称: | GLYCEROL, GTPase NRas, MAGNESIUM ION, ... | | 著者 | Reid, D, Johnson, C, Salter, S, Mattos, C. | | 登録日 | 2017-01-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | | 主引用文献 | The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects.
J. Biol. Chem., 292, 2017
|
|
8A67
 | |
7NBB
 | |
7NPO
 | | Branched K48-K63-Ub3 | | 分子名称: | GLYCEROL, Polyubiquitin-B | | 著者 | Lange, S.M, Kwasna, D, Kulathu, Y. | | 登録日 | 2021-02-27 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Nat.Struct.Mol.Biol., 2024
|
|
8BN2
 | | Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with D-Serine | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Heroven, C, Malinauskas, T, Aricescu, A.R. | | 登録日 | 2022-11-11 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | GluD1 binds GABA and controls inhibitory plasticity.
Science, 382, 2023
|
|
8BN5
 | | Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Heroven, C, Malinauskas, T, Aricescu, A.R. | | 登録日 | 2022-11-12 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | GluD1 binds GABA and controls inhibitory plasticity.
Science, 382, 2023
|
|
8BLJ
 | | Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1), apo state | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Heroven, C, Malinauskas, T, Aricescu, A.R. | | 登録日 | 2022-11-09 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | GluD1 binds GABA and controls inhibitory plasticity.
Science, 382, 2023
|
|
5UFJ
 | | Crystal Structure of Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Complexed with GBT Compound 6 | | 分子名称: | 5-[(imidazo[1,2-a]pyridin-8-yl)methoxy]-2-methoxypyridine-4-carbaldehyde, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | | 著者 | Partridge, J.R, Choy, R.M, Li, Z, Metcalf, B. | | 登録日 | 2017-01-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.
ACS Med Chem Lett, 8, 2017
|
|
5JSJ
 | |
5JSG
 | |
6QDJ
 | | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | | 分子名称: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Meinhart, A, Clausen, T, Arnese, R. | | 登録日 | 2019-01-02 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.884 Å) | | 主引用文献 | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
|
|
6QDL
 | |
6QDM
 | |
6QDK
 | |
5U3I
 | | CRYSTAL STRUCTURE OF CARBONMONOXY HEMOGLOBIN S (LIGANDED SICKLE CELL HEMOGLOBIN) COMPLEXED WITH GBT compound 31 | | 分子名称: | 2-methoxy-5-({2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}methoxy)pyridine-4-carbaldehyde, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | | 著者 | Partridge, J.R, Choy, R.M, Li, Z, Metcalf, B. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.
ACS Med Chem Lett, 8, 2017
|
|
6MDU
 | | Crystal structure of NDM-1 with compound 7 | | 分子名称: | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide, GLYCEROL, Metallo-beta-lactamase type 2, ... | | 著者 | Akhtar, A, Chen, Y. | | 登録日 | 2018-09-05 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery.
Acs Infect Dis., 5, 2019
|
|
