8BN5

Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA

Summary for 8BN5

Entry DOI	10.2210/pdb8bn5/pdb
Descriptor	Glutamate receptor ionotropic, delta-1, CALCIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	ion channel, ligand binding domain, glutamate receptor, gaba, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	63499.63
Authors	Heroven, C.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2022-11-12, release date: 2023-11-22, Last modification date: 2024-01-03)
Primary citation	Piot, L.,Heroven, C.,Bossi, S.,Zamith, J.,Malinauskas, T.,Johnson, C.,Wennagel, D.,Stroebel, D.,Charrier, C.,Aricescu, A.R.,Mony, L.,Paoletti, P. GluD1 binds GABA and controls inhibitory plasticity. Science, 382:1389-1394, 2023 Cited by PubMed: 38060673 DOI: 10.1126/science.adf3406 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation