8BN5

Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glutamate receptor ionotropic, delta-1	polymer	282	31347.4	2	UniProt (Q9ULK0) Pfam (PF10613) Pfam (PF00060)	Homo sapiens (human)	GluD1,GluR delta-1 subunit
2	C, I, J (A, B)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
3	D, K (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	F, L (A, B)	GAMMA-AMINO-BUTANOIC ACID	non-polymer		103.1	2	Chemie (ABU)
6	G, H, M (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
7	N, O (A, B)	water	water		18.0	225	Chemie (HOH)

Sequence modifications

A, B: 436 - 547 (UniProt: Q9ULK0)
A, B: 664 - 823 (UniProt: Q9ULK0)

PDB	External Database	Details
Gly 548	-	linker
Thr 549	-	linker
Gly 824	-	expression tag
Thr 825	-	expression tag
Leu 826	-	expression tag
Glu 827	-	expression tag
Val 828	-	expression tag
Leu 829	-	expression tag
Phe 830	-	expression tag
Gln 831	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62694.8
Non-Polymers*	Number of molecules	11
	Total formula weight	804.8
All*	Total formula weight	63499.6

*Water molecules are not included.