8DDZ
| TEM-1 beta-lactamase A237Y | 分子名称: | Beta-lactamase TEM | 著者 | Ji, Z, Boxer, S.G, Mathews, I.I. | 登録日 | 2022-06-19 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of beta-Lactamases. J.Am.Chem.Soc., 144, 2022
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8DE1
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8DE2
| TEM-1 beta-lactamase A237Y mutant covalently bound to avibactam, a room temperature structure | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase TEM | 著者 | Ji, Z, Boxer, S.G, Mathews, I.I. | 登録日 | 2022-06-19 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of beta-Lactamases. J.Am.Chem.Soc., 144, 2022
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8DE0
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7U6Q
| TEM-1 beta-lactamase | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Ji, Z, Boxer, S.G, Mathews, I.I. | 登録日 | 2022-03-04 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of beta-Lactamases. J.Am.Chem.Soc., 144, 2022
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6J69
| Structure of KIBRA and Dendrin Complex | 分子名称: | Peptide from Dendrin, Protein KIBRA | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-01-14 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | 主引用文献 | Kibra Modulates Learning and Memory via Binding to Dendrin. Cell Rep, 26, 2019
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6J68
| Structure of KIBRA and LATS1 Complex | 分子名称: | Peptide from Serine/threonine-protein kinase LATS1, Protein KIBRA | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-01-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6JJY
| Crystal Structure of KIBRA and beta-Dystroglycan | 分子名称: | Peptide from Dystroglycan, Protein KIBRA, SULFATE ION | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6JK0
| Crystal Structure of YAP1 and Dendrin complex | 分子名称: | CALCIUM ION, Transcriptional coactivator YAP1,Dendrin | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6JK1
| Crystal Structure of YAP1 and Dendrin complex 2 | 分子名称: | Dendrin,Transcriptional coactivator YAP1 | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6JJW
| Crystal Structure of KIBRA and PTPN14 complex | 分子名称: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6JJZ
| Crystal Structure of MAGI2 and Dendrin complex | 分子名称: | ACETATE ION, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | 著者 | Lin, Z, Zhang, H, Yang, Z, Ji, Z, Zhang, M, Zhu, J. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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6OA9
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
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6OAA
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
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6OAB
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
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6JJX
| Crystal Structure of KIBRA and Angiomotin complex | 分子名称: | Peptide from Angiomotin, Protein KIBRA | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
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7LJE
| Discovery of Spirohydantoins as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases | 分子名称: | 2-[4-[(3'R,4S)-3'-fluoro-1-[2-[(4-fluorophenyl)methyl-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]amino]-2-oxo-ethyl]-2,5-dioxo-spiro[imidazolidine-4,1'-indane]-5'-yl]pyrazol-1-yl]-N-methyl-acetamide, Histone acetyltransferase p300 | 著者 | Jakob, C.G. | 登録日 | 2021-01-29 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.607 Å) | 主引用文献 | Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases. Bioorg.Med.Chem.Lett., 39, 2021
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6CHS
| Cdc48-Npl4 complex in the presence of ATP-gamma-S | 分子名称: | MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. | 登録日 | 2018-02-22 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
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5DH3
| Crystal structure of MST2 in complex with XMU-MP-1 | 分子名称: | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, CHLORIDE ION, SULFATE ION, ... | 著者 | Kong, L.L, Yun, C.H. | 登録日 | 2015-08-29 | 公開日 | 2016-08-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.468 Å) | 主引用文献 | Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration Sci Transl Med, 8, 2016
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7VCU
| Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCT
| Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCX
| Human p97 single hexamer conformer II with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCS
| Human p97 double hexamer conformer II with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-03 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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7VCV
| Human p97 single hexamer conformer I with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | 登録日 | 2021-09-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
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5U8F
| Polycomb protein EED in complex with inhibitor: (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine | 分子名称: | (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine, Polycomb protein EED | 著者 | Jakob, C.G, Zhu, H. | 登録日 | 2016-12-14 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.343 Å) | 主引用文献 | SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding. Bioorg. Med. Chem. Lett., 27, 2017
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