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5W45
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Crystal structure of APOBEC3H
分子名称: APOBEC3H, ZINC ION
著者Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S.
登録日2017-06-09
公開日2018-03-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.
Sci Rep, 8, 2018
9ASK
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Human DNA polymerase theta helicase domain dimer, apo-form
分子名称: DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
9C5Q
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Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-06-06
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
9ASL
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Human DNA polymerase theta helicase domain tetramer, apo-form
分子名称: DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
9ASJ
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Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
分子名称: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
8E40
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Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, RNA, ...
著者Ito, F, Alvarez-Cabrera, A.L, Liu, S, Yang, H, Shiriaeva, A, Zhou, Z.H, Chen, X.S.
登録日2022-08-17
公開日2023-01-11
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase.
Sci Adv, 9, 2023
8FVJ
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Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5
分子名称: Core-binding factor subunit beta, Cullin-5, Elongin-B, ...
著者Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
登録日2023-01-19
公開日2023-09-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
8FVI
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Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5
分子名称: Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ...
著者Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
登録日2023-01-19
公開日2023-09-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
8UD3
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SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form
分子名称: Non-structural protein 15, RNA (35-MER)
著者Ito, F, Yang, H, Zhou, Z.H, Chen, X.S.
登録日2023-09-28
公開日2024-04-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
8UD4
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SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1
分子名称: Non-structural protein 15, RNA (35-MER)
著者Ito, F, Yang, H, Zhou, Z.H, Chen, X.S.
登録日2023-09-28
公開日2024-04-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
8UD2
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SARS-CoV-2 Nsp15, apo-form
分子名称: Non-structural protein 15
著者Ito, F, Yang, H, Zhou, Z.H, Chen, X.S.
登録日2023-09-28
公開日2024-04-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
8UD5
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SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2
分子名称: Non-structural protein 15, RNA (35-MER)
著者Ito, F, Yang, H, Zhou, Z.H, Chen, X.S.
登録日2023-09-28
公開日2024-04-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
8W0A
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BU of 8w0a by Molmil
Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-13
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
5BPV
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BU of 5bpv by Molmil
Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A
分子名称: Polymerase cofactor VP35
著者Fadda, V, Cannas, V, Zinzula, L, Distinto, S, Daino, G.L, Bianco, G, Corona, A, Esposito, F, Alcaro, S, Maccioni, E, Tramontano, E, Taylor, G.L.
登録日2015-05-28
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A
to be published
1XYX
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mouse prion protein fragment 121-231
分子名称: Major prion protein
著者Gossert, A.D, Bonjour, S, Lysek, D.A, Fiorito, F, Wuthrich, K.
登録日2004-11-11
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Prion protein NMR structures of elk and of mouse/elk hybrids
Proc.Natl.Acad.Sci.USA, 102, 2005
1Y16
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mouse prion protein with mutations S170N and N174T
分子名称: Major prion protein
著者Gossert, A.D, Bonjour, S, Lysek, D.A, Fiorito, F, Wuthrich, K.
登録日2004-11-17
公開日2005-01-25
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Prion protein NMR structures of elk and of mouse/elk hybrids
Proc.Natl.Acad.Sci.Usa, 102, 2005
1XYW
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elk prion protein
分子名称: Major prion protein
著者Gossert, A.D, Bonjour, S, Lysek, D.A, Fiorito, F, Wuthrich, K.
登録日2004-11-11
公開日2004-12-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Prion protein NMR structures of elk and of mouse/elk hybrids
Proc.Natl.Acad.Sci.Usa, 102, 2005
1XYJ
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NMR Structure of the cat prion protein
分子名称: prion protein
著者Lysek, D.A, Schorn, C, Nivon, L.G, Esteve-Moya, V, Christen, B, Calzolai, L, von Schroetter, C, Fiorito, F, Herrmann, T, Guntert, P.
登録日2004-11-10
公開日2005-01-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Prion protein NMR structures of cats, dogs, pigs, and sheep
Proc.Natl.Acad.Sci.USA, 102, 2005
1Y15
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Mouse Prion Protein with mutation N174T
分子名称: Major prion protein
著者Gossert, A.D, Bonjour, S, Lysek, D.A, Fiorito, F, Wuthrich, K.
登録日2004-11-17
公開日2004-12-28
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Prion protein NMR structures of elk and of mouse/elk hybrids
Proc.Natl.Acad.Sci.Usa, 102, 2005
1PN5
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NMR structure of the NALP1 Pyrin domain (PYD)
分子名称: NACHT-, LRR- and PYD-containing protein 2
著者Hiller, S, Kohl, A, Fiorito, F, Herrmann, T, Wider, G, Tschopp, J, Grutter, M.G, Wuthrich, K.
登録日2003-06-12
公開日2003-10-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
Structure, 11, 2003
1K91
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Solution Structure of Calreticulin P-domain subdomain (residues 221-256)
分子名称: CALRETICULIN
著者Ellgaard, L, Bettendorff, P, Braun, D, Herrmann, T, Fiorito, F, Guntert, P, Helenius, A, Wuthrich, K.
登録日2001-10-26
公開日2002-10-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structures of 36 and 73-residue Fragments of the Calreticulin P-domain
J.Mol.Biol., 322, 2002
1K9C
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BU of 1k9c by Molmil
Solution Structure of Calreticulin P-domain subdomain (residues 189-261)
分子名称: CALRETICULIN
著者Ellgaard, L, Bettendorff, P, Braun, D, Herrmann, T, Fiorito, F, Guntert, P, Helenius, A, Wuthrich, K.
登録日2001-10-29
公開日2002-10-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structures of 36 and 73-residue Fragments of the Calreticulin P-domain
J.Mol.Biol., 322, 2002
2ZDU
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BU of 2zdu by Molmil
Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
分子名称: 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid, Mitogen-activated protein kinase 10
著者Sogabe, S, Ohra, T, Itoh, F, Habuka, N, Fujishima, A.
登録日2007-11-27
公開日2008-09-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1)
Bioorg.Med.Chem., 16, 2008
6P3X
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Crystal Structure of Full Length APOBEC3G E/Q (pH 7.0)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P3Z
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Crystal Structure of Full Length APOBEC3G E/Q (pH 5.2)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.844 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020

 

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