8JX3
| alpha-Hemolysin(G122S/K147R/K237C)-SpyTag/SpyCatcher head to head 14-mer | 分子名称: | alpha hemolysin fused with spy-catcher, alpha hemolysin fused with spy-tag | 著者 | Ishii, Y, Naito, K, Yokoyama, T, Tanaka, Y, Matsuura, T. | 登録日 | 2023-06-30 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | alpha-Hemolysin(G122S/K147R)-SpyTag/SpyCatcher head to head 14-mer To Be Published
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8JX2
| alpha-Hemolysin(G122S/K147R)-SpyTag/SpyCatcher head to head 14-mer | 分子名称: | alpha hemolysin fused with spy-catcher, alpha hemolysin fused with spy-tag | 著者 | Ishii, Y, Naito, K, Yokoyama, T, Tanaka, Y, Matsuura, T. | 登録日 | 2023-06-30 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | alpha-Hemolysin(G122S/K147R)-SpyTag/SpyCatcher head to head 14-mer To Be Published
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4WBG
| Crystal structure of class C beta-lactamase Mox-1 covalently complexed with aztorenam | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, ACETATE ION, Beta-lactamase, ... | 著者 | Oguri, T, Shimizu-ibuka, A, Ishii, Y. | 登録日 | 2014-09-03 | 公開日 | 2015-07-01 | 最終更新日 | 2020-01-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational Change Observed in the Active Site of Class C beta-Lactamase MOX-1 upon Binding to Aztreonam Antimicrob.Agents Chemother., 59, 2015
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2MXU
| 42-Residue Beta Amyloid Fibril | 分子名称: | Amyloid beta A4 protein | 著者 | Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. | 登録日 | 2015-01-14 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLID-STATE NMR | 主引用文献 | A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22, 2015
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1BZA
| BETA-LACTAMASE TOHO-1 FROM ESCHERICHIA COLI TUH12191 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Ibuka, A, Taguchi, A, Ishiguro, M, Fushinobu, S, Ishii, Y, Kamitori, S, Okuyama, K, Yamaguchi, K, Konno, M, Matsuzawa, H. | 登録日 | 1998-10-28 | 公開日 | 1999-04-27 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution. J.Mol.Biol., 285, 1999
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6BN3
| CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | 著者 | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | 登録日 | 2017-11-16 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.278 Å) | 主引用文献 | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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6BPF
| CTX-M-151 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 Angstrom resolution | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | 著者 | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | 登録日 | 2017-11-23 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.318 Å) | 主引用文献 | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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5B3R
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1IYS
| Crystal Structure of Class A beta-Lactamase Toho-1 | 分子名称: | BETA-LACTAMASE TOHO-1, SULFATE ION | 著者 | Ibuka, A.S, Ishii, Y, Yamaguchi, K, Matsuzawa, H, Sakai, H. | 登録日 | 2002-09-06 | 公開日 | 2003-10-14 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal Structure of Extended-Spectrum beta-Lactamase Toho-1: Insights into the Molecular Mechanism for
Catalytic Reaction and Substrate Specificity Expansion Biochemistry, 42, 2003
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1IYO
| Toho-1 beta-Lactamase In Complex With Cefotaxime | 分子名称: | CEFOTAXIME, C3' cleaved, open, ... | 著者 | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | 登録日 | 2002-09-04 | 公開日 | 2002-12-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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1IYP
| Toho-1 beta-Lactamase In Complex With Cephalothin | 分子名称: | CEPHALOTHIN GROUP, SULFATE ION, Toho-1 beta-lactamase | 著者 | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | 登録日 | 2002-09-04 | 公開日 | 2002-12-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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1IYQ
| Toho-1 beta-Lactamase In Complex With Benzylpenicillin | 分子名称: | OPEN FORM - PENICILLIN G, SULFATE ION, Toho-1 beta-lactamase | 著者 | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | 登録日 | 2002-09-04 | 公開日 | 2002-12-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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2ZQD
| Ceftazidime acyl-intermediate structure of class a beta-lact Toho-1 E166A/R274N/R276N triple mutant | 分子名称: | ACYLATED CEFTAZIDIME, Beta-lactamase Toho-1, SULFATE ION | 著者 | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | 登録日 | 2008-08-07 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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2ZQC
| Aztreonam acyl-intermediate structure of class a beta-lactam Toho-1 E166A/R274N/R276N triple mutant | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1, SULFATE ION | 著者 | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | 登録日 | 2008-08-07 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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3W8K
| Crystal structure of class C beta-lactamase Mox-1 | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Shimizu-ibuka, A, Oguri, T, Furuyama, T, Ishii, Y. | 登録日 | 2013-03-15 | 公開日 | 2014-04-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of Mox-1, a unique plasmid-mediated class C beta-lactamase with hydrolytic activity towards moxalactam Antimicrob.Agents Chemother., 58, 2014
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2ZQA
| Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant | 分子名称: | Beta-lactamase Toho-1, CEFOTAXIME, C3' cleaved, ... | 著者 | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | 登録日 | 2008-08-07 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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2ZQ9
| Cephalothin acyl-intermediate structure of class a beta-lactamase Toho-1 E166A/R274N/R276N triple mutant | 分子名称: | 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase Toho-1, CEPHALOTHIN, ... | 著者 | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | 登録日 | 2008-08-07 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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1DCJ
| SOLUTION STRUCTURE OF YHHP, A NOVEL ESCHERICHIA COLI PROTEIN IMPLICATED IN THE CELL DIVISION | 分子名称: | YHHP PROTEIN | 著者 | Katoh, E, Hatta, T, Shindo, H, Mizuno, T, Yamazaki, T. | 登録日 | 1999-11-05 | 公開日 | 2001-07-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division. J.Mol.Biol., 304, 2000
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5ZYB
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5BOH
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2DDQ
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6AAV
| Crystal structure of alpha-glucosyl transfer enzyme, XgtA at 1.72 angstrom resolution | 分子名称: | Alpha-glucosyltransferase | 著者 | Kurumizaka, H, Arimura, Y, Kirimura, K, Watanabe, R. | 登録日 | 2018-07-19 | 公開日 | 2019-07-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of alpha-glucosyl transfer enzyme XgtA from Xanthomonas campestris WU-9701. Biochem.Biophys.Res.Commun., 526, 2020
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7VVI
| OXA-58 crystal structure of acylated meropenem complex | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, SULFATE ION | 著者 | Saino, H, Sugiyabu, T, Miyano, M. | 登録日 | 2021-11-06 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | OXA-58 crystal structure of acylated meropenem complex to be published
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7XMC
| Cryo-EM structure of Cytochrome bo3 from Escherichia coli, apo structure with DMSO | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | 著者 | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | 登録日 | 2022-04-25 | 公開日 | 2022-12-21 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7XMD
| Cryo-EM structure of Cytochrome bo3 from Escherichia coli, the structure complexed with an allosteric inhibitor N4 | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | 著者 | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | 登録日 | 2022-04-25 | 公開日 | 2022-12-21 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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