4Z9I
 
 | | Asp-TarS from E. coli | | 分子名称: | ASPARTIC ACID, Methyl-accepting chemotaxis protein II | | 著者 | Mise, T. | | 登録日 | 2015-04-10 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli
Biochemistry, 55, 2016
|
|
4Z9H
 | | Asp-Tar from E. coli | | 分子名称: | ASPARTIC ACID, Methyl-accepting chemotaxis protein II | | 著者 | Mise, T. | | 登録日 | 2015-04-10 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.452 Å) | | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli
Biochemistry, 55, 2016
|
|
4Z9J
 | | Apo-Tar from E. coli | | 分子名称: | Methyl-accepting chemotaxis protein II | | 著者 | Mise, T. | | 登録日 | 2015-04-10 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Analysis of the Ligand-Binding Domain of the Aspartate Receptor Tar from Escherichia coli
Biochemistry, 55, 2016
|
|
3HRX
 | |
1NXN
 | | SOLUTION STRUCTURE OF CONTRYPHAN-VN | | 分子名称: | CONTRYPHAN-VN, MAJOR FORM (CIS CONFORMER) | | 著者 | Eliseo, T, Cicero, D.O, Polticelli, F, Schinina, M.E, Massilia, G.R, Paci, M, Ascenzi, P. | | 登録日 | 2003-02-11 | | 公開日 | 2003-03-04 | | 最終更新日 | 2020-06-24 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator
Biopolymers, 74, 2004
|
|
2JN3
 | | NMR structure of cl-BABP complexed to chenodeoxycholic acid | | 分子名称: | CHENODEOXYCHOLIC ACID, Fatty acid-binding protein, liver | | 著者 | Eliseo, T, Ragona, L, Catalano, M, Assfalf, M, Paci, M, Zetta, L, Molinari, H, Cicero, D.O. | | 登録日 | 2006-12-22 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR
Biochemistry, 46, 2007
|
|
5JHQ
 | |
1ZZF
 | |
2K1Q
 | | NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor | | 分子名称: | NS3 PROTEASE, PHENETHYLAMIDE, ZINC ION | | 著者 | Eliseo, T, Gallo, M, Pennestri, M, Bazzo, R, Cicero, D.O. | | 登録日 | 2008-03-13 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.
J.Mol.Biol., 385, 2009
|
|
8HLB
 | | Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | | 分子名称: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | | 著者 | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | | 登録日 | 2022-11-29 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Commun Biol, 6, 2023
|
|
6YQN
 | | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW9 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-aminophenyl)-4-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]t rideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]benzamide | | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-04-17 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Int.J.Cancer, 147, 2020
|
|
6YQP
 | | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW22 | | 分子名称: | (~{E})-3-[4-[[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6 ),4,7,10,12-pentaen-9-yl]ethanoylamino]methyl]phenyl]-~{N}-oxidanyl-prop-2-enamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-04-17 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Int.J.Cancer, 147, 2020
|
|
6YQO
 | | Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor TW12 | | 分子名称: | (S)-N1-(4-(2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)phenyl)-N8-hydroxyoctanediamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | 著者 | Joerger, A.C, Balourdas, D.I, Weiser, T, Chatterjee, D, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-04-17 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Int.J.Cancer, 147, 2020
|
|
2MNQ
 | | 1H, 13C, and 15N Chemical Shift Assignments for Thymosin alpha 1 | | 分子名称: | THYMOSIN ALPHA-1 | | 著者 | Nepravishta, R, Mandaliti, W, Eliseo, T, Sinibaldi Vallebona, P, Pica, F, Garaci, E, Paci, M. | | 登録日 | 2014-04-09 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Thymosin alpha 1 inserts N terminus into model membranes assuming a helical conformation.
Expert Opin Biol Ther, 15 Suppl 1, 2015
|
|
2OII
 | | Structure of EMILIN-1 C1q-like domain | | 分子名称: | EMILIN-1 | | 著者 | Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G. | | 登録日 | 2007-01-11 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the C-terminal domain of EMILIN-1
To be Published
|
|
2K6L
 | | The solution structure of XACb0070 from Xanthonomas axonopodis pv citri reveals this new protein is a member of the RHH family of transcriptional repressors | | 分子名称: | Putative uncharacterized protein | | 著者 | Gallo, M, Cicero, D.O, Amata, I, Eliseo, T, Paci, M, Spisni, A, Ferrari, E, Pertinhez, T.A, Farah, C.S. | | 登録日 | 2008-07-11 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure reveals that XACb0070 from the plant pathogen Xanthomonas citri belongs to the RHH superfamily of bacterial DNA-binding proteins
To be Published
|
|
2KA3
 | | Structure of EMILIN-1 C1Q-like domain | | 分子名称: | EMILIN-1 | | 著者 | Verdone, G, Corazza, A, Colebrooke, S.A, Cicero, D.O, Eliseo, T, Boyd, J, Doliana, R, Fogolari, F, Viglino, P, Colombatti, A, Campbell, I.D, Esposito, G. | | 登録日 | 2008-10-30 | | 公開日 | 2008-11-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1
J.Biomol.Nmr, 43, 2009
|
|
6FE6
 | | Solution structure of a last generation P2-P4 macrocyclic inhibitor | | 分子名称: | (3aR,7S,10S,12R,24aR)-7-cyclopentyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-5,8-dioxo-1,2,3,3a,5,6,7,8,11,12,20,21,22,23,24,24a-hexadecahydro-10H-9,12-methanocyclopenta[18,19][1,10,3,6]dioxadiazacyclononadecino[12,11-b]quinoline-10-carboxamide, Non-structural 3 protease, ZINC ION | | 著者 | Gallo, M, Eliseo, T, Cicero, D.O. | | 登録日 | 2017-12-29 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a last generation macrocyclic inhibitor. Hepatitis C virus NS3 protease complex: when S prime region occupancy is not enough to stabilize the protein conformation in the absence of NS4A.
To Be Published
|
|
1R8P
 | |
1ZRY
 | | NMR structural analysis of apo chicken liver bile acid binding protein | | 分子名称: | Fatty acid-binding protein, liver | | 著者 | Ragona, L, Catalano, M, Luppi, M, Cicero, D, Eliseo, T, Foote, J, Fogolari, F, Zetta, L, Molinari, H. | | 登録日 | 2005-05-23 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Dynamic Studies Suggest that Allosteric Activation Regulates Ligand Binding in Chicken Liver Bile Acid-binding Protein
J.Biol.Chem., 281, 2006
|
|
8YX1
 | | CD40 in complex with Bleselumab Fab | | 分子名称: | Bleselumab, heavy chain, light chain, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2024-04-01 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
|
|
8YX9
 | | CD40 in complex with Dacetuzumab Fab | | 分子名称: | Dacetuzumab, Heavy chain, light chain, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2024-04-02 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
|
|
6DFJ
 | |
8EKD
 | |
8FGX
 | | Cryo-EM structure of the STAR-0215 Fab in complex with active human plasma kallikrein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein light chain, STAR-0215 Heavy chain, ... | | 著者 | Fuller, J.R, Biris, N, Bista, P. | | 登録日 | 2022-12-13 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | STAR-0215 is a Novel, Long-Acting Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Potential Treatment of Hereditary Angioedema.
J.Pharmacol.Exp.Ther., 387, 2023
|
|
