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4UPG
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BU of 4upg by Molmil
X-ray structure of calcium-free human sorcin
分子名称: DI(HYDROXYETHYL)ETHER, SORCIN, SULFATE ION
著者Ilari, A, Fiorillo, A, Colotti, G.
登録日2014-06-16
公開日2014-06-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of Sorcin-Mediated Calcium-Dependent Signal Transduction.
Sci.Rep., 5, 2015
1GVH
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BU of 1gvh by Molmil
The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unespected geometry of the distal heme pocket
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, FLAVOHEMOPROTEIN, ...
著者Ilari, A, Johnson, K.A, Bonamore, A, Farina, A, Boffi, A.
登録日2002-02-13
公開日2002-08-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The X-Ray Structure of Ferric Escherichia Coli Flavohemoglobin Reveals an Unexpected Geometry of the Distal Heme Pocket
J.Biol.Chem., 277, 2002
4USL
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BU of 4usl by Molmil
The X-ray structure of calcium bound human sorcin
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, SORCIN, ...
著者Ilari, A, Fiorillo, A, Colotti, G.
登録日2014-07-10
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Sorcin-Mediated Calcium-Dependent Signal Transduction.
Sci.Rep., 5, 2015
1GJY
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BU of 1gjy by Molmil
The X-ray structure of the Sorcin Calcium Binding Domain (SCBD) provides insight into the phosphorylation and calcium dependent processess
分子名称: SORCIN, SULFATE ION
著者Ilari, A, Johnson, K.A, Nastopoulos, V, Tsernoglou, D, Chiancone, E.
登録日2001-08-06
公開日2002-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of the Sorcin Calcium Binding Domain Provides a Model of Ca(2+)-Dependent Processes in the Full-Length Protein
J.Mol.Biol., 317, 2002
2VNE
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BU of 2vne by Molmil
The X-ray structure of Norcoclaurine synthase from Thalictrum flavum
分子名称: S-NORCOCLAURINE SYNTHASE
著者Ilari, A, Franceschini, S, Boffi, A, Bonamore, A, Pasquo, A.
登録日2008-02-04
公開日2008-08-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis.
J.Biol.Chem., 284, 2009
1QGH
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BU of 1qgh by Molmil
THE X-RAY STRUCTURE OF THE UNUSUAL DODECAMERIC FERRITIN FROM LISTERIA INNOCUA, REVEALS A NOVEL INTERSUBUNIT IRON BINDING SITE.
分子名称: FE (III) ION, NON-HEME IRON-CONTAINING FERRITIN
著者Ilari, A, Stefanini, S, Chiancone, E, Tsernoglou, D.
登録日1999-04-27
公開日2000-01-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site.
Nat.Struct.Biol., 7, 2000
2VQ5
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BU of 2vq5 by Molmil
X-ray structure of Norcoclaurine synthase from Thalictrum flavum in complex with dopamine and hydroxybenzaldehyde
分子名称: ACETATE ION, CHLORIDE ION, L-DOPAMINE, ...
著者Ilari, A, Franceschini, S, Bonamore, A, Boffi, A.
登録日2008-03-11
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis.
J.Biol.Chem., 284, 2009
2UZZ
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BU of 2uzz by Molmil
X-ray structure of N-methyl-L-tryptophan oxidase (MTOX)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-METHYL-L-TRYPTOPHAN OXIDASE, SODIUM ION
著者Ilari, A, Fiorillo, A, Franceschini, S, Bonamore, A, Colotti, G, Boffi, A.
登録日2007-05-03
公開日2008-01-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The X-Ray Structure of N-Methyltryptophan Oxidase Reveals the Structural Determinants of Substrate Specificity.
Proteins, 71, 2008
2VY0
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BU of 2vy0 by Molmil
The X-ray structure of endo-beta-1,3-glucanase from Pyrococcus furiosus
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
著者Ilari, A, Fiorillo, A.
登録日2008-07-15
公開日2009-03-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal Structure of a Family 16 Endoglucanase from the Hyperthermophile Pyrococcus Furiosus-Structural Basis of Substrate Recognition.
FEBS J., 276, 2009
2BJY
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BU of 2bjy by Molmil
The X-ray crystal structure of Listeria innocua Dps H31G-H43G mutant.
分子名称: NON-HEME IRON-CONTAINING FERRITIN
著者Ilari, A, Stefanini, S, Chiancone, E.
登録日2005-02-08
公開日2005-02-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Unusual Intersubunit Ferroxidase Center of Listeria Innocua Dps is Required for Hydrogen Peroxide Detoxification But not for Iron Uptake. A Study with Site-Specific Mutants
Biochemistry, 44, 2005
2BKC
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BU of 2bkc by Molmil
The X-ray structure of the H43G Listeria innocua Dps mutant
分子名称: NON-HEME IRON-CONTAINING FERRITIN
著者Ilari, A, Stefanini, S, Chiancone, E.
登録日2005-02-15
公開日2005-02-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The unusual intersubunit ferroxidase center of Listeria innocua Dps is required for hydrogen peroxide detoxification but not for iron uptake. A study with site-specific mutants.
Biochemistry, 44, 2005
2BK6
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BU of 2bk6 by Molmil
The X-ray crystal structure of the Listeria innocua H31G Dps mutant.
分子名称: NON-HEME IRON-CONTAINING FERRITIN
著者Ilari, A, Latella, M.C, Ribacchi, F, Su, M, Giangiacomo, L, Stefanini, S, Chasteen, N.D, Chiancone, E.
登録日2005-02-11
公開日2005-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The unusual intersubunit ferroxidase center of Listeria innocua Dps is required for hydrogen peroxide detoxification but not for iron uptake. A study with site-specific mutants.
Biochemistry, 44, 2005
2BKM
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BU of 2bkm by Molmil
Crystal structure of the truncated hemoglobin from Geobacillus stearothermophilus
分子名称: ACETATE ION, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ilari, A, Kjelgaard, P, von Wachenfeldt, C, Boffi, A, Chiancone, E.
登録日2006-02-08
公開日2006-11-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure and Ligand Binding Properties of the Truncated Hemoglobin from Geobacillus Stearothermophilus
Arch.Biochem.Biophys., 457, 2007
6RB5
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BU of 6rb5 by Molmil
Trypanothione reductase in complex with 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide
分子名称: 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Ilari, A, Fiorillo, A, Battista, T, Mocci, S.
登録日2019-04-09
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.977 Å)
主引用文献Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.
Plos Negl Trop Dis, 14, 2020
6ER5
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BU of 6er5 by Molmil
X-ray structure of Trypanothione Reductase from Leishmania infantum in complex with 2-(diethylamino)ethyl 4-((3-(4-nitrophenyl)-3-oxopropyl)amino)benzoate
分子名称: 2-(diethylamino)ethyl 4-((3-(4-nitrophenyl)-3-oxopropyl)amino)benzoate, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Ilari, A, Fiorillo, A.
登録日2017-10-17
公開日2018-10-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.
Plos Negl Trop Dis, 12, 2018
5M3U
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BU of 5m3u by Molmil
The X-ray structure of human V216F phosphoglycerate kinase 1 mutant
分子名称: 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ilari, A, Fiorillo, A, Cipollone, A, Petrosino, M.
登録日2016-10-17
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS ONE, 13, 2018
4U8D
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BU of 4u8d by Molmil
X-ray structure of Mg-bound human sorcin
分子名称: MAGNESIUM ION, Sorcin
著者Fiorillo, A, Ilari, A, Colotti, G.
登録日2014-08-02
公開日2015-08-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献INVESTIGATING THE CONFORMATIONAL CHANGES of SORCIN TO SHED LIGHT ON SIGNAL TRANSDUCTION IN THE APOPTOTIC PROCESS
To be published
4K1F
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BU of 4k1f by Molmil
Crystal structure of reduced tryparedoxin peroxidase from leishmania major at 2.34 A resolution
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ilari, A, Fiorillo, A, Di Chiaro, F.
登録日2013-04-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking
Sci Rep, 5, 2015
6Y75
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BIL2 domain from T.thermophila BUBL1 locus (C1A-N143A)
分子名称: DI(HYDROXYETHYL)ETHER, FORMIC ACID, NAD(P)(+)--arginine ADP-ribosyltransferase, ...
著者Ilari, A, Chiarini, V.
登録日2020-02-28
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of ubiquitination mediated by protein splicing in early Eukarya.
Biochim Biophys Acta Gen Subj, 1865, 2021
1O9R
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BU of 1o9r by Molmil
The X-ray crystal structure of Agrobacterium tumefaciens Dps, a member of the family that protect DNA without binding
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AGROBACTERIUM TUMEFACIENS DPS, ...
著者Ilari, A, Ceci, P, Chiancone, E.
登録日2002-12-18
公開日2003-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Dps Protein of Agrobacterium Tumefaciens Does not Bind to DNA But Protects It Toward Oxidative Cleavage: X-Ray Crystal Structure, Iron Binding, and Hydroxyl-Radical Scavenging Properties
J.Biol.Chem., 278, 2003
1UX8
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X-ray structure of truncated oxygen-avid haemoglobin from Bacillus subtilis
分子名称: CHLORIDE ION, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ilari, A, Giangiacomo, L, Boffi, A, Chiancone, E.
登録日2004-02-20
公開日2004-12-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Truncated Oxygen-Avid Hemoglobin from Bacillus Subtilis: X-Ray Structure and Ligand Binding Properties
J.Biol.Chem., 280, 2005
5EBK
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BU of 5ebk by Molmil
Trypanothione reductase in complex with 6-(sec-butoxy)-2-((3-chlorophenyl)thio)pyrimidin-4-amine
分子名称: 6-sec-Butoxy-2-[(3-chlorophenyl)sulfanyl]-4-pyrimidinamine, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Ilari, A, Angiulli, G.
登録日2015-10-19
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives.
J Enzyme Inhib Med Chem, 32, 2017
2YAU
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X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin
分子名称: 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Baiocco, P, Ilari, A, Colotti, G.
登録日2011-02-24
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A Gold-Containing Drug Against Parasitic Polyamine Metabolism: The X-Ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Auranofin Reveals a Dual Mechanism of Enzyme Inhibition.
Amino Acids, 42, 2012
1UVH
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X-ray structure of Dps from Mycobacterium smegmatis
分子名称: FE (III) ION, STARVATION-INDUCED DNA PROTECTING PROTEIN
著者Ilari, A, Ceci, P, Falvo, E, Chiancone, E.
登録日2004-01-20
公開日2005-02-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Reassessment of Protein Stability, DNA Binding, and Protection of Mycobacterium Smegmatis Dps.
J.Biol.Chem., 280, 2005
2XY4
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X-RAY STRUCTURE OF ZNUA-WT FROM SALMONELLA ENTERICA
分子名称: SULFATE ION, TRIETHYLENE GLYCOL, ZINC ABC TRANSPORTER, ...
著者Alaleona, F, Ilari, A, Battistoni, A, Petrarca, P, Chiancone, E.
登録日2010-11-15
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The X-Ray Structure of the Zinc Transporter Znua from Salmonella Enterica Discloses a Unique Triad of Zinc Coordinating Histidines.
J.Mol.Biol., 409, 2011

 

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