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6H05
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BU of 6h05 by Molmil
Cryo-electron microscopic structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex [residues 218-453]
分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
著者Nagy, B, Zambo, Z, Hubert, A, Polak, M, Nemeria, N.S, Novacek, J, Jordan, F, Adam-Vizi, V, Ambrus, A.
登録日2018-07-06
公開日2020-01-22
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure.
Biochim Biophys Acta Gen Subj, 1865, 2021
6I4S
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BU of 6i4s by Molmil
Crystal structure of the disease-causing R447G mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Hubert, A, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
6I4U
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BU of 6i4u by Molmil
Crystal structure of the disease-causing G426E mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Hubert, A, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
4YO1
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BU of 4yo1 by Molmil
Structure of Legionella pneumophila DegQ (delta PDZ2 variant)
分子名称: CADMIUM ION, DegQ
著者Wrase, R, Hilgenfeld, R, Hansen, G.
登録日2015-03-11
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States.
J.Mol.Biol., 427, 2015
4YNN
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BU of 4ynn by Molmil
Structure of Legionella pneumophila DegQ (S190A variant)
分子名称: Hepta-peptide, Hexa-peptide, Octapeptide, ...
著者Wrase, R, Hilgenfeld, R, Hansen, G.
登録日2015-03-10
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States.
J.Mol.Biol., 427, 2015
3TXM
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BU of 3txm by Molmil
Crystal structure of Rpn6 from Drosophila melanogaster, Gd(3+) complex
分子名称: 26S proteasome regulatory complex subunit p42B, GADOLINIUM ION, SULFATE ION
著者Pathare, G.R, Bracher, A.
登録日2011-09-23
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TXN
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BU of 3txn by Molmil
Crystal structure of Rpn6 from Drosophila melanogaster, native data
分子名称: 26S proteasome regulatory complex subunit p42B, GLYCEROL, SULFATE ION
著者Pathare, G.R, Bracher, A.
登録日2011-09-23
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.
Proc.Natl.Acad.Sci.USA, 109, 2012
5M86
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BU of 5m86 by Molmil
Crystal Structure of the Thermoplasma acidophilum Protein Ta1207
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Pathare, G.R, Nagy, I, Bracher, A.
登録日2016-10-28
公開日2017-06-14
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Thermoplasma acidophilum protein Ta1207.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6I4P
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BU of 6i4p by Molmil
Crystal structure of the disease-causing G194C mutant of the human dihydrolipoamide dehydrogenase
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, mitochondrial, ...
著者Szabo, E, Wilk, P, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
6I4R
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BU of 6i4r by Molmil
Crystal structure of the disease-causing R460G mutant of the human dihydrolipoamide dehydrogenase at 1.44 Angstrom resolution
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, mitochondrial, ...
著者Szabo, E, Wilk, P, Bui, D, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.439 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
6I4T
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BU of 6i4t by Molmil
Crystal structure of the disease-causing I445M mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
6I4Q
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BU of 6i4q by Molmil
Crystal structure of the human dihydrolipoamide dehydrogenase at 1.75 Angstrom resolution
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, mitochondrial, ...
著者Nagy, B, Szabo, E, Wilk, P, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
6I4Z
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BU of 6i4z by Molmil
Crystal structure of the disease-causing P453L mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-12
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.342 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
5CAW
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BU of 5caw by Molmil
Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
分子名称: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, SULFATE ION, ...
著者Wauer, T, Komander, D.
登録日2015-06-30
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
5C9V
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BU of 5c9v by Molmil
Structure of human Parkin G319A
分子名称: E3 ubiquitin-protein ligase parkin, GLYCEROL, SULFATE ION, ...
著者Wauer, T, Komander, D.
登録日2015-06-29
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015

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件を2024-07-17に公開中

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