Structure of human Parkin G319A

Summary for 5C9V

DescriptorE3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsparkin, ubiquitin, e3 ligase, rbr, parkinson's disease, mitophagy, cell signalling, signaling protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm, cytosol  O60260
Total number of polymer chains1
Total molecular weight38268.06
Wauer, T.,Komander, D. (deposition date: 2015-06-29, release date: 2015-07-22, Last modification date: 2017-09-13)
Primary citation
Wauer, T.,Simicek, M.,Schubert, A.,Komander, D.
Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524:370-374, 2015
PubMed: 26161729 (PDB entries with the same primary citation)
DOI: 10.1038/nature14879
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.230300.4%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5c9v
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Molmil generated image of 5c9v
rotated about x axis by 90°
Molmil generated image of 5c9v
rotated about y axis by 90°