7EV4
 
 | | Crystal structure of the Lon-like protease MtaLonC with S582A mutation in complex with F-b20-Q | | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-20 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7EV6
 | | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with F-b20-Q | | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-20 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7EUY
 | | Crystal structure of the Lon-like protease MtaLonC with D582A mutation in complex with substrate polypeptide | | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-19 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7EUX
 | | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with substrate polypeptide | | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | | 登録日 | 2021-05-19 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
8K3Y
 | | The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | | 登録日 | 2023-07-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7F3V
 | | Crystal structure of YfiH with C107A mutation in complex with endogenous UDP-MurNAc | | 分子名称: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... | | 著者 | Lee, M.S, Hsieh, K.Y, Chang, C.I. | | 登録日 | 2021-06-17 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural Basis for the Peptidoglycan-Editing Activity of YfiH.
Mbio, 13, 2021
|
|
7W1G
 | | Crystal structure of YfiH with C107A mutation in complex with UDP-MurNAc-L-Serine | | 分子名称: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, (2S)-2-[[(2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2-[[[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-6-(hydroxymethyl)-5-oxidanyl-oxan-4-yl]oxypropanoyl]amino]-3-oxidanyl-propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Lee, S.H, Hsieh, K.Y, Lee, M.S, Chang, C.I. | | 登録日 | 2021-11-19 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural Basis for the Peptidoglycan-Editing Activity of YfiH.
Mbio, 13, 2021
|
|
7YPJ
 | | Spiral pentamer of the substrate-free Lon protease with a S678A mutation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-03 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YPK
 | | Close-ring hexamer of the substrate-bound Lon protease with an S678A mutation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, alpha-S1-casein | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-03 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YPI
 | | Spiral hexamer of the substrate-free Lon protease with a Y224S mutation | | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-03 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YPH
 | | Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation | | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-03 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
8IKR
 | |
6WQH
 | | Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ... | | 著者 | Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C. | | 登録日 | 2020-04-28 | | 公開日 | 2021-06-09 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease.
J.Biol.Chem., 297, 2021
|
|
7FD4
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | 登録日 | 2021-07-16 | | 公開日 | 2021-11-03 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
|
|
7FD5
 | | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | | 登録日 | 2021-07-16 | | 公開日 | 2021-11-03 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
|
|
7FID
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon proteasecomplex (conformation 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | 登録日 | 2021-07-31 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7FIZ
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | 登録日 | 2021-08-01 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7FIE
 | | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | | 登録日 | 2021-07-31 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
|
|
7YUU
 | | MtaLon-ADP for the spiral oligomers of trimer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUV
 | | MtaLon-ADP for the spiral oligomers of tetramer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUW
 | | MtaLon-ADP for the spiral oligomers of pentamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-18 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUM
 | | MtaLon-Apo for the spiral oligomers of tetramer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUH
 | | MtaLon-Apo for the spiral oligomers of trimer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUP
 | | MtaLon-Apo for the spiral oligomers of pentamer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7YUT
 | | MtaLon-Apo for the spiral oligomers of hexamer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
