7W1G

Crystal structure of YfiH with C107A mutation in complex with UDP-MurNAc-L-Serine

Summary for 7W1G

Entry DOI	10.2210/pdb7w1g/pdb
Descriptor	Purine nucleoside phosphorylase YfiH, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, SULFATE ION, ... (7 entities in total)
Functional Keywords	hydrolase, duf152, amidase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	113011.21
Authors	Lee, S.H.,Hsieh, K.Y.,Lee, M.S.,Chang, C.I. (deposition date: 2021-11-19, release date: 2021-12-29, Last modification date: 2023-11-29)
Primary citation	Lee, M.S.,Hsieh, K.Y.,Kuo, C.I.,Lee, S.H.,Garde, S.,Reddy, M.,Chang, C.I. Structural Basis for the Peptidoglycan-Editing Activity of YfiH. Mbio, 13:-, 2021 Cited by PubMed: 35164571 DOI: 10.1128/mbio.03646-21 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation