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1Z1A
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BU of 1z1a by Molmil
S. cerevisiae Sir1 ORC-interaction domain
分子名称: Regulatory protein SIR1
著者Hou, Z, Bernstein, D.A, Fox, C.A, Keck, J.L.
登録日2005-03-03
公開日2005-06-07
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1KKB
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BU of 1kkb by Molmil
Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin
分子名称: Adenylosuccinate Synthetase, HADACIDIN, INOSINIC ACID
著者Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B.
登録日2001-12-06
公開日2002-03-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
1KKF
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BU of 1kkf by Molmil
Complex of E. coli Adenylosuccinate Synthetase with IMP, Hadacidin, Pyrophosphate, and Mg
分子名称: Adenylosuccinate Synthetase, DIPHOSPHATE, HADACIDIN, ...
著者Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B.
登録日2001-12-07
公開日2002-03-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
1KJX
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BU of 1kjx by Molmil
IMP Complex of E. Coli Adenylosuccinate Synthetase
分子名称: Adenylosuccinate Synthetase, INOSINIC ACID
著者Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B.
登録日2001-12-05
公開日2002-03-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
5VJX
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BU of 5vjx by Molmil
Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor
分子名称: CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H.
登録日2017-04-20
公開日2017-12-06
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
5VJI
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BU of 5vji by Molmil
Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor
分子名称: CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H.
登録日2017-04-19
公開日2017-06-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
1ZHI
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BU of 1zhi by Molmil
Complex of the S. cerevisiae Orc1 and Sir1 interacting domains
分子名称: Origin recognition complex subunit 1, Regulatory protein SIR1
著者Hou, Z, Bernstein, D.A, Fox, C.A, Keck, J.L.
登録日2005-04-25
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3VAY
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BU of 3vay by Molmil
Crystal structure of 2-Haloacid Dehalogenase from Pseudomonas syringae pv. Tomato DC3000
分子名称: HAD-superfamily hydrolase, IODIDE ION, MAGNESIUM ION
著者Hou, Z, Zhang, H, Li, M, Chang, W.
登録日2011-12-30
公開日2013-01-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Structure of 2-haloacid dehalogenase from Pseudomonas syringae pv. tomato DC3000
Acta Crystallogr.,Sect.D, 69, 2013
1CH8
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BU of 1ch8 by Molmil
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH A STRINGENT EFFECTOR, PPG2':3'P
分子名称: GUANOSINE 5'-DIPHOSPHATE 2':3'-CYCLIC MONOPHOSPHATE, HADACIDIN, INOSINIC ACID, ...
著者Hou, Z, Cashel, M, Fromm, H.J, Honzatko, R.B.
登録日1999-03-31
公開日1999-12-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
1CIB
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BU of 1cib by Molmil
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH GDP, IMP, HADACIDIN, AND NO3
分子名称: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ...
著者Hou, Z, Cashel, M, Fromm, H.J, Honzatko, R.B.
登録日1999-03-31
公開日2000-04-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
8YRF
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BU of 8yrf by Molmil
Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenyl-cysteine
分子名称: 1,2-ETHANEDIOL, Transcriptional regulator, PadR-like family
著者Zhou, Z, Huang, W.
登録日2024-03-21
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenyl-cysteine
To Be Published
5WTW
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BU of 5wtw by Molmil
Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group
分子名称: CHLORIDE ION, Core protein
著者Zhou, Z, Xu, Z.H.
登録日2016-12-15
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
5T2P
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BU of 5t2p by Molmil
Hepatitis B virus core protein Y132A mutant in complex with sulfamoylbenzamide (SBA_R01)
分子名称: 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide, CHLORIDE ION, Core protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2016-08-24
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.693 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
5WRE
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BU of 5wre by Molmil
Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01)
分子名称: (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2016-12-01
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
2QJU
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BU of 2qju by Molmil
Crystal Structure of an NSS Homolog with Bound Antidepressant
分子名称: 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, LEUCINE, ...
著者Zhou, Z, Karpowich, N.K, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2007-07-09
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
Science, 317, 2007
2RPI
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BU of 2rpi by Molmil
The NMR structure of the submillisecond folding intermediate of the Thermus thermophilus ribonuclease H
分子名称: Ribonuclease H
著者Zhou, Z, Feng, H, Bai, Y.
登録日2008-05-16
公開日2009-03-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H
J.Mol.Biol., 384, 2008
2L5A
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BU of 2l5a by Molmil
Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3
分子名称: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
著者Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y.
登録日2010-10-28
公開日2011-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
7CI3
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BU of 7ci3 by Molmil
The crystal structure of the SARS-CoV-2 ORF7a ectodomain
分子名称: Orf7a protein
著者Zhou, Z, Zhou, Z, Chen, S.
登録日2020-07-07
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14 + monocytes.
Iscience, 24, 2021
3GWU
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BU of 3gwu by Molmil
Leucine transporter LeuT in complex with sertraline
分子名称: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, LEUCINE, SODIUM ION, ...
著者Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
登録日2009-04-01
公開日2009-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
3GWW
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BU of 3gww by Molmil
Leucine transporter LeuT in complex with S-fluoxetine
分子名称: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ...
著者Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
登録日2009-04-01
公開日2009-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
3GWV
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BU of 3gwv by Molmil
Leucine transporter LeuT in complex with R-fluoxetine
分子名称: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ...
著者Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
登録日2009-04-01
公開日2009-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
2L5V
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BU of 2l5v by Molmil
Solution structure of the C-terminal domain of hRpn13
分子名称: Proteasomal ubiquitin receptor ADRM1
著者Zhou, Z, Hu, H.
登録日2010-11-08
公開日2011-11-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal domain of hRpn13
To be Published
7XGN
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BU of 7xgn by Molmil
Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Nicotinic Acid (NA)
分子名称: CHLORIDE ION, NICOTINIC ACID, Quinolinate Phosphoribosyl Transferase, ...
著者Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z.
登録日2022-04-05
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis.
Acs Chem.Biol., 18, 2023
7XGL
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BU of 7xgl by Molmil
Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in Apo form
分子名称: CHLORIDE ION, GLYCEROL, Quinolinate Phosphoribosyl Transferase, ...
著者Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z.
登録日2022-04-05
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis.
Acs Chem.Biol., 18, 2023
7XGM
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BU of 7xgm by Molmil
Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Quinolinic Acid (QA)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, QUINOLINIC ACID, ...
著者Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z.
登録日2022-04-05
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis.
Acs Chem.Biol., 18, 2023

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