1JB7
 
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5I9J
 | | Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | | 分子名称: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | | 著者 | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | | 登録日 | 2016-02-20 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein.
Acta Crystallogr.,Sect.F, 72, 2016
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1OTC
 | | THE O. NOVA TELOMERE END BINDING PROTEIN COMPLEXED WITH SINGLE STRAND DNA | | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3'), PROTEIN (TELOMERE-BINDING PROTEIN ALPHA SUBUNIT), PROTEIN (TELOMERE-BINDING PROTEIN BETA SUBUNIT) | | 著者 | Horvath, M.P, Schweiker, V.L, Bevilacqua, J.M, Ruggles, J.A, Schultz, S.C. | | 登録日 | 1998-11-25 | | 公開日 | 1999-04-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA.
Cell(Cambridge,Mass.), 95, 1998
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2I0Q
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6Q0C
 | | MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with undamaged dG | | 分子名称: | 1,2-ETHANEDIOL, A/G-specific adenine glycosylase, CALCIUM ION, ... | | 著者 | O'Shea Murray, V.L, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2019-08-01 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
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6U7T
 | | MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) | | 分子名称: | Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | | 著者 | O'Shea Murray, V.L, Cao, S, Horvath, M.P, David, S.S. | | 登録日 | 2019-09-03 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
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3FP6
 | | Anionic trypsin in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.49 A resolution limit | | 分子名称: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2009-01-04 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3FP7
 | | Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit | | 分子名称: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2009-01-04 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3FP8
 | | Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.46 A resolution limit | | 分子名称: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P, Curtice, K. | | 登録日 | 2009-01-04 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
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8DVP
 | | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine | | 分子名称: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | | 著者 | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2022-07-29 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
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8DW0
 | | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site (AP) product and crystallized with sodium acetate | | 分子名称: | 1,2-ETHANEDIOL, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | | 著者 | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2022-07-30 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
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8DW7
 | | DNA glycosylase MutY variant N146S in complex with DNA containing the transition state analog 1N paired with d(8-oxo-G) | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | | 著者 | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2022-07-31 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
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8DVY
 | | DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate | | 分子名称: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | | 著者 | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2022-07-30 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
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8DW4
 | | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an abasic site product (AP) generated by the enzyme in crystals by removal of calcium | | 分子名称: | ACETATE ION, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | | 著者 | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | | 登録日 | 2022-07-31 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
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8DWD
 | | Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine | | 分子名称: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | | 著者 | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | | 登録日 | 2022-08-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
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8DWF
 | | Glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with substrate adenine | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | | 著者 | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | | 登録日 | 2022-08-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
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8DWE
 | | Adenine glycosylase MutY variant E43Q in complex with DNA containing d(8-oxo-G) paired with substrate purine | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | | 著者 | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | | 登録日 | 2022-08-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
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1Y62
 | | A 2.4 crystal structure of conkunitzin-S1, a novel Kunitz-fold cone snail neurotoxin. | | 分子名称: | Conkunitzin-S1, SULFATE ION | | 著者 | Dy, C.Y, Buczek, P, Horvath, M.P. | | 登録日 | 2004-12-03 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail.
Acta Crystallogr.,Sect.D, 62, 2006
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2FI5
 | | Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2005-12-27 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
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2FI4
 | | Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2005-12-27 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
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2FTL
 | | Crystal structure of trypsin complexed with BPTI at 100K | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2006-01-24 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin.
J.Mol.Biol., 366, 2007
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2FTM
 | | Crystal structure of trypsin complexed with the BPTI variant (Tyr35->Gly) | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2006-01-24 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin.
J.Mol.Biol., 366, 2007
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2FI3
 | | Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2005-12-27 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
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2M7R
 | | Nmda receptor antagonist, conantokin bk-b, nmr, 20 structure | | 分子名称: | CONANTOKIN BK-B | | 著者 | Curtice, K.J, Platt, R.J, Skalicky, J.J, Horvath, M.P, Twede, V.D. | | 登録日 | 2013-04-29 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes.
Toxicon, 81C, 2014
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8FAY
 | | Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) | | 分子名称: | Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ... | | 著者 | Trasvina-Arenas, C.H, Lin, W.J, Demir, M, Fisher, A.J, David, S.S, Horvath, M.P. | | 登録日 | 2022-11-29 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
To Be Published
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