3TMN
 
 | |
5TMN
 | | Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues | | 分子名称: | CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ... | | 著者 | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | | 登録日 | 1987-06-29 | | 公開日 | 1989-01-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
|
|
1Z24
 | | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution. | | 分子名称: | BILIVERDIN IX GAMMA CHROMOPHORE, Insecticyanin A form | | 著者 | Holden, H.M, Rypniewski, W.R, Law, J.H, Rayment, I. | | 登録日 | 2005-03-07 | | 公開日 | 2005-04-05 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution.
Embo J., 6, 1987
|
|
4TMN
 | | SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES | | 分子名称: | CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ... | | 著者 | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | | 登録日 | 1987-06-29 | | 公開日 | 1989-01-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
|
|
1TLK
 | |
1EI6
 | | CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE | | 分子名称: | L(+)-TARTARIC ACID, PHOSPHONOACETATE HYDROLASE, PHOSPHONOFORMIC ACID, ... | | 著者 | Holden, H.M, Benning, M.M, Dunaway-Mariano, D, Kim, A.D. | | 登録日 | 2000-02-24 | | 公開日 | 2003-11-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Phosphonoacetate Hydrolase complexed with phosphonoformate
To be Published
|
|
5T6B
 | | X-ray structure of the KijD1 C3-methyltransfeerase, converted to monomeric form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, S-ADENOSYL-L-HOMOCYSTEINE, Sugar 3-C-methyl transferase, ... | | 著者 | Holden, H.M, Thoden, J.B, Dow, G.T. | | 登録日 | 2016-09-01 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural studies on KijD1, a sugar C-3'-methyltransferase.
Protein Sci., 25, 2016
|
|
5T67
 | | x-ray structure of the KijD1 C3-methyltransferase from Actinomadura kijaniata in complex with SAH and dTDP-sugar product | | 分子名称: | (2R,4S,6R)-4-amino-4,6-dimethyl-5-oxotetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Holden, H.M, Thoden, J.B, Dow, G.T. | | 登録日 | 2016-09-01 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural studies on KijD1, a sugar C-3'-methyltransferase.
Protein Sci., 25, 2016
|
|
5T64
 | | X-ray structure of the C3-methyltransferase KijD1 from Actinomadura kijaniata in complex with TDP and SAH | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Holden, H.M, Thoden, J.B, DOW, G.T. | | 登録日 | 2016-09-01 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural studies on KijD1, a sugar C-3'-methyltransferase.
Protein Sci., 25, 2016
|
|
4HMZ
 | | Crystal Structure of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP-quinovose | | 分子名称: | 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate | | 著者 | Holden, H.M, Kubiak, R.L. | | 登録日 | 2012-10-18 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
|
|
4HN0
 | |
4HN1
 | | Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP | | 分子名称: | 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, THYMIDINE, ... | | 著者 | Holden, H.M, Kubiak, R.L. | | 登録日 | 2012-10-18 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
|
|
3GR9
 | | Crystal structure of ColD H188K S187N | | 分子名称: | 2-OXOGLUTARIC ACID, ColD | | 著者 | Holden, H.M, Cook, P.D, Kubiak, R.L, Toomey, D.P. | | 登録日 | 2009-03-25 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Two Site-Directed Mutations Are Required for the Conversion of a Sugar Dehydratase into an Aminotransferase.
Biochemistry, 48, 2009
|
|
3BXO
 | | Crystal Structure of Streptomyces venezuelae DesVI | | 分子名称: | 1,2-ETHANEDIOL, N,N-dimethyltransferase, PHENYL-URIDINE-5'-DIPHOSPHATE, ... | | 著者 | Holden, H.M, Burgie, E.S. | | 登録日 | 2008-01-14 | | 公開日 | 2008-03-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-Dimensional Structure of DesVI from Streptomyces venezuelae: A Sugar N,N-Dimethyltransferase Required for dTDP-Desosamine Biosynthesis.
Biochemistry, 47, 2008
|
|
4KCF
 | | X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose | | 分子名称: | FAD-dependent oxidoreductase, FLAVIN MONONUCLEOTIDE, [(2R,4S,6R)-4-azanyl-4,6-dimethyl-5,5-bis(oxidanyl)oxan-2-yl] [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | | 著者 | Holden, H.M, Thoden, J.B, Branch, M.C, Zimmer, A.L, Bruender, N.A. | | 登録日 | 2013-04-24 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | Active site architecture of a sugar N-oxygenase.
Biochemistry, 52, 2013
|
|
3ETJ
 | | Crystal structure E. coli Purk in complex with Mg, ADP, and Pi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROGENPHOSPHATE ION, ... | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2008-10-08 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
|
|
3NYU
 | |
3NYT
 | | X-ray crystal structure of the WlbE (WpbE) aminotransferase from pseudomonas aeruginosa, mutation K185A, in complex with the PLP external aldimine adduct with UDP-3-amino-2-N-acetyl-glucuronic acid, at 1.3 angstrom resolution | | 分子名称: | (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name), Aminotransferase WbpE, SODIUM ION | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2010-07-15 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.301 Å) | | 主引用文献 | Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase.
Protein Sci., 26, 2017
|
|
3NYS
 | |
3OA0
 | | Crystal structure of the WlbA (WbpB) Dehydrogenase from Thermus thermophilus in complex with NAD and UDP-GlcNAcA | | 分子名称: | (2S,3S,4R,5R,6R)-5-acetamido-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4-dihydroxy-oxane-2-carboxylic acid, CHLORIDE ION, Lipopolysaccharide biosynthesis protein wbpB, ... | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2010-08-04 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Studies of WlbA: A Dehydrogenase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid .
Biochemistry, 49, 2010
|
|
3O9Z
 | | Crystal structure of the WlbA (WbpB) dehydrogenase from Thermus thermophilus in complex with NAD and alpha-ketoglutarate at 1.45 angstrom resolution | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2010-08-04 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Structural and Functional Studies of WlbA: A Dehydrogenase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid .
Biochemistry, 49, 2010
|
|
3DR7
 | | GDP-perosamine synthase from Caulobacter crescentus with bound GDP-3-deoxyperosamine | | 分子名称: | (2R,3S,5S,6R)-5-amino-3-hydroxy-6-methyl-oxan-2-yl, 1,2-ETHANEDIOL, Putative perosamine synthetase | | 著者 | Holden, H.M, Cook, P.D, Carney, A.E. | | 登録日 | 2008-07-10 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
|
|
3OA2
 | |
3DR4
 | | GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand | | 分子名称: | 1,2-ETHANEDIOL, Putative perosamine synthetase, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate | | 著者 | Holden, H.M, Cook, P.D, Carney, A.E. | | 登録日 | 2008-07-10 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
|
|
3ETH
 | | Crystal structure of E. coli Purk in complex with MgATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2008-10-08 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
|
|
