4TMN
 
 | | SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES | | 分子名称: | CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ... | | 著者 | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | | 登録日 | 1987-06-29 | | 公開日 | 1989-01-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
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1Z24
 | | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution. | | 分子名称: | BILIVERDIN IX GAMMA CHROMOPHORE, Insecticyanin A form | | 著者 | Holden, H.M, Rypniewski, W.R, Law, J.H, Rayment, I. | | 登録日 | 2005-03-07 | | 公開日 | 2005-04-05 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution.
Embo J., 6, 1987
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5TMN
 | | Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues | | 分子名称: | CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ... | | 著者 | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | | 登録日 | 1987-06-29 | | 公開日 | 1989-01-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
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3TMN
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1TLK
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1EI6
 | | CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE | | 分子名称: | L(+)-TARTARIC ACID, PHOSPHONOACETATE HYDROLASE, PHOSPHONOFORMIC ACID, ... | | 著者 | Holden, H.M, Benning, M.M, Dunaway-Mariano, D, Kim, A.D. | | 登録日 | 2000-02-24 | | 公開日 | 2003-11-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Phosphonoacetate Hydrolase complexed with phosphonoformate
To be Published
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4HMZ
 | | Crystal Structure of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP-quinovose | | 分子名称: | 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate | | 著者 | Holden, H.M, Kubiak, R.L. | | 登録日 | 2012-10-18 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
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4HN0
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4HN1
 | | Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP | | 分子名称: | 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, THYMIDINE, ... | | 著者 | Holden, H.M, Kubiak, R.L. | | 登録日 | 2012-10-18 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
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4J7G
 | | Crystal structure of EvaA, a 2,3-dehydratase in complex with dTDP-fucose and dTDP-rhamnose | | 分子名称: | 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, EvaA 2,3-dehydratase, [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate | | 著者 | Holden, H.M, Kubiak, R.L, Thoden, J.B. | | 登録日 | 2013-02-13 | | 公開日 | 2013-05-22 | | 最終更新日 | 2013-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
Biochemistry, 52, 2013
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4J7H
 | | Crystal structure of EvaA, a 2,3-dehydratase in complex with dTDP-benzene and dTDP-rhamnose | | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ... | | 著者 | Holden, H.M, Kubiak, R.L, Thoden, J.B. | | 登録日 | 2013-02-13 | | 公開日 | 2013-05-22 | | 最終更新日 | 2013-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
Biochemistry, 52, 2013
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3BXO
 | | Crystal Structure of Streptomyces venezuelae DesVI | | 分子名称: | 1,2-ETHANEDIOL, N,N-dimethyltransferase, PHENYL-URIDINE-5'-DIPHOSPHATE, ... | | 著者 | Holden, H.M, Burgie, E.S. | | 登録日 | 2008-01-14 | | 公開日 | 2008-03-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-Dimensional Structure of DesVI from Streptomyces venezuelae: A Sugar N,N-Dimethyltransferase Required for dTDP-Desosamine Biosynthesis.
Biochemistry, 47, 2008
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5K8C
 | | X-ray structure of KdnB, 3-deoxy-alpha-D-manno-octulosonate 8-oxidase, from Shewanella oneidensis | | 分子名称: | 1,2-ETHANEDIOL, 3-deoxy-alpha-D-manno-octulosonate 8-oxidase, CHLORIDE ION, ... | | 著者 | Holden, H.M, Thoden, J.B, Zachman-Brockmeyer, T.R. | | 登録日 | 2016-05-28 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid.
Biochemistry, 55, 2016
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5K8B
 | | X-ray structure of KdnA, 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase, from Shewanella oneidensis in the presence of the external aldimine with PLP and glutamate | | 分子名称: | 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase, CHLORIDE ION, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID, ... | | 著者 | Holden, H.M, Thoden, J.B, Zachman-Brockmeyer, T.R. | | 登録日 | 2016-05-28 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid.
Biochemistry, 55, 2016
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5KF8
 | | X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum in complex with glucosamine | | 分子名称: | 1,2-ETHANEDIOL, 2-amino-2-deoxy-beta-D-glucopyranose, 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, ... | | 著者 | Holden, H.M, Thoden, J.B, Dopkins, B.J, Tipton, P.A. | | 登録日 | 2016-06-12 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase.
Biochemistry, 55, 2016
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4KCF
 | | X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose | | 分子名称: | FAD-dependent oxidoreductase, FLAVIN MONONUCLEOTIDE, [(2R,4S,6R)-4-azanyl-4,6-dimethyl-5,5-bis(oxidanyl)oxan-2-yl] [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | | 著者 | Holden, H.M, Thoden, J.B, Branch, M.C, Zimmer, A.L, Bruender, N.A. | | 登録日 | 2013-04-24 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | Active site architecture of a sugar N-oxygenase.
Biochemistry, 52, 2013
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3ETJ
 | | Crystal structure E. coli Purk in complex with Mg, ADP, and Pi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROGENPHOSPHATE ION, ... | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2008-10-08 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
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3DR7
 | | GDP-perosamine synthase from Caulobacter crescentus with bound GDP-3-deoxyperosamine | | 分子名称: | (2R,3S,5S,6R)-5-amino-3-hydroxy-6-methyl-oxan-2-yl, 1,2-ETHANEDIOL, Putative perosamine synthetase | | 著者 | Holden, H.M, Cook, P.D, Carney, A.E. | | 登録日 | 2008-07-10 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
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3DR4
 | | GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand | | 分子名称: | 1,2-ETHANEDIOL, Putative perosamine synthetase, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate | | 著者 | Holden, H.M, Cook, P.D, Carney, A.E. | | 登録日 | 2008-07-10 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
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3ETH
 | | Crystal structure of E. coli Purk in complex with MgATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit | | 著者 | Holden, H.M, Thoden, J.B. | | 登録日 | 2008-10-08 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
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3GR9
 | | Crystal structure of ColD H188K S187N | | 分子名称: | 2-OXOGLUTARIC ACID, ColD | | 著者 | Holden, H.M, Cook, P.D, Kubiak, R.L, Toomey, D.P. | | 登録日 | 2009-03-25 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Two Site-Directed Mutations Are Required for the Conversion of a Sugar Dehydratase into an Aminotransferase.
Biochemistry, 48, 2009
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5KF1
 | | X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum, apo form, pH 5 | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, COENZYME A, ... | | 著者 | Holden, H.M, Thoden, J.B, Dopkins, B.J, tipton, P.A. | | 登録日 | 2016-06-11 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase.
Biochemistry, 55, 2016
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5KF2
 | | X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum, apo form, pH 8 | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, COENZYME A, ... | | 著者 | Holden, H.M, Thoden, J.B, Dopkins, B.J, Tipton, P.A. | | 登録日 | 2016-06-11 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase.
Biochemistry, 55, 2016
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3OA2
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3NYS
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