7Z68
 
 | | Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured) | | 分子名称: | (2~{R})-~{N}-[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanylphenyl]-3-phenyl-2-sulfanyl-propanamide, CALCIUM ION, GLYCEROL, ... | | 著者 | Klein, A, Hirsch, A. | | 登録日 | 2022-03-11 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB
To Be Published
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8A9C
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8A8Y
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4V67
 | | Crystal structure of a translation termination complex formed with release factor RF2. | | 分子名称: | 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... | | 著者 | Korostelev, A, Asahara, H, Lancaster, L, Laurberg, M, Hirschi, A, Noller, H.F. | | 登録日 | 2008-10-27 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of a translation termination complex formed with release factor RF2.
Proc.Natl.Acad.Sci.USA, 105, 2008
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4LPA
 | | Crystal structure of a Cdc6 phosphopeptide in complex with Cks1 | | 分子名称: | Cyclin-dependent kinases regulatory subunit | | 著者 | McGrath, D.A, Balog, E.R.M, Koivomagi, M, Lucena, R, Mai, M.V, Hirschi, A, Kellogg, D.R, Loog, M, Rubin, S.M. | | 登録日 | 2013-07-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Cks confers specificity to phosphorylation-dependent CDK signaling pathways.
Nat.Struct.Mol.Biol., 20, 2013
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3N5U
 | | Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Retinoblastoma-associated protein, ... | | 著者 | Hirschi, A.M, Cecchini, M, Steinhardt, R.C, Dick, F.A, Rubin, S.M. | | 登録日 | 2010-05-25 | | 公開日 | 2010-08-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
Nat.Struct.Mol.Biol., 17, 2010
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4XBF
 | | Structure of LSD1:CoREST in complex with ssRNA | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Luka, Z, Loukachevitch, L.V, Martin, W.J, Wagner, C, Reiter, N.J. | | 登録日 | 2014-12-16 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme.
RNA, 22, 2016
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5OJE
 | | Endothiapepsin with Ligand VSK-B24 | | 分子名称: | (2~{S})-2-azanyl-3-(1~{H}-indol-3-yl)-~{N}-[2-(2,4,6-trimethylphenyl)ethyl]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... | | 著者 | Gierse, R.M, Magari, F, Groves, M.R, Heine, A, Klebe, G, Hirsch, A. | | 登録日 | 2017-07-21 | | 公開日 | 2018-09-12 | | 最終更新日 | 2018-11-21 | | 実験手法 | X-RAY DIFFRACTION (1.579 Å) | | 主引用文献 | Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin.
ChemMedChem, 13, 2018
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8A29
 | | Apo 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa | | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Hamid, R, Adam, S, Lacour, A, Monjas, L, Hirsch, A. | | 登録日 | 2022-06-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
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8A4D
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8A45
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8A5K
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7ZOC
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7N40
 | | Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex | | 分子名称: | Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog | | 著者 | Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. | | 登録日 | 2021-06-02 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Nat Commun, 13, 2022
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