7ZOC

Crystal structure of the peptidase domain of collagenase H from Clostridium histolyticum in complex with N-aryl-2-alkylmercaptoacetamide-based inhibitor

Summary for 7ZOC

• Entry DOI: 10.2210/pdb7zoc/pdb
• Related: 5o7e
• Descriptor: Collagenase ColH, ZINC ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: collagenase, inhibitor, complex, hydrolase
• Biological source: Hathewaya histolytica
• Total number of polymer chains: 1
• Total formula weight: 48422.92

Authors

Schoenauer, E.,Brandstetter, H. (deposition date: 2022-04-25, release date: 2023-05-10, Last modification date: 2024-02-07)

• Primary citation: Schoenauer, E.,Brandstetter, H.; N-aryl-2-iso-butylmercaptoacetamides: the discovery of highly potent and selective inhibitors of P. aeruginosa virulence factor LasB and C. histolyticum virulence factor ColH; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.91 Å)