8A4D

1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with a thiamine analog inhibitor

Summary for 8A4D

Entry DOI	10.2210/pdb8a4d/pdb
Descriptor	1-deoxy-D-xylulose-5-phosphate synthase, 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}ethanol, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	transferase
Biological source	Pseudomonas aeruginosa LESB58 More
Total number of polymer chains	6
Total formula weight	405354.63
Authors	Hamid, R.,Hirsch, A. (deposition date: 2022-06-10, release date: 2023-07-12, Last modification date: 2024-02-07)
Primary citation	Hamid, R.,Adam, S.,Lacour, A.,Monjas, L.,Kohnke, J.,Hirsch, A.K.H. 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding. J.Biol.Chem., 299:105152-105152, 2023 Cited by PubMed: 37567475 DOI: 10.1016/j.jbc.2023.105152 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation